Prof. Dr. med. Özgür Yaldizli

Durrer, Alicia, Wolleb, Julia, Bieder, Florentin, Friedrich, Paul, Melie-Garcia, Lester, Ocampo Pineda, Mario Alberto, Bercea, Cosmin I., Hamamci, Ibrahim Ethem, Wiestler, Benedikt, Piraud, Marie, Yaldizli, Oezguer, Granziera, Cristina, Menze, Bjoern, Cattin, Philippe C., & Kofler, Florian. (2025). Denoising Diffusion Models for 3D Healthy Brain Tissue Inpainting. 15224 LNCS, 87–97. https://doi.org/10.1007/978-3-031-72744-3_9

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1- A Pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in Multiple Sclerosis: a study protocol for a randomized clinical trial [Posted-content]. In medRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.22.24304720

Benkert, Pascal, Maleska Maceski, Aleksandra, Schaedelin, Sabine, Oechtering, Johanna, Zadic, Amar, Vilchez Gomez, Juan Francisco, Melie-Garcia, Lester, Cagol, Alessandro, Galbusera, Riccardo, Subramaniam, Suvitha, Lorscheider, Johannes, Galli, Edoardo, Mueller, Jannis, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Findling, Oliver, Lalive, Patrice H., Bridel, Claire, Uginet, Marjolaine, et al. (2024). Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels Reflect Different Mechanisms of Disease Progression under B-Cell Depleting Treatment in Multiple Sclerosis. Annals of Neurology. https://doi.org/10.1002/ana.27096

Cagol, Alessandro, Benkert, Pascal, Melie-Garcia, Lester, Schaedelin, Sabine A., Leber, Selina, Tsagkas, Charidimos, Barakovic, Muhamed, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Ruberte, Esther, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Lorscheider, Johannes, D’Souza, Marcus, Fischer-Barnicol, Bettina, Muller, Stefanie, Achtnichts, Lutz, et al. (2024). Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS. Neurology, 102. https://doi.org/10.1212/wnl.0000000000207768

Cortese, Rosa, Battaglini, Marco, Prados, Ferran, Gentile, Giordano, Luchetti, Ludovico, Bianchi, Alessia, Haider, Lukas, Jacob, Anu, Palace, Jacqueline, Messina, Silvia, Paul, Friedemann, Marignier, Romain, Durand-Dubief, Françoise, de Medeiros Rimkus, Carolina, Apostolos Pereira, Samira Luisa, Sato, Douglas Kazutoshi, Filippi, Massimo, Rocca, M.A., Cacciaguerra, Laura, et al. (2024). Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis. Annals of Neurology, 96, 276–288. https://doi.org/10.1002/ana.26951

Hench, J., Hultschig, C., Bratic Hench, I., Sadasivan, H., Yaldizli, Ö., Hutter, G., Dirnhofer, S., Tzankov, A., & Frank, S. (2024). Rapid brain lymphoma diagnostics through nanopore sequencing of cytology-negative cerebrospinal fluid. Acta Neuropathologica, 148. https://doi.org/10.1007/s00401-024-02793-z

Hirt, Julian, Janiaud, Perrine, Düblin, Pascal, Nicoletti, Giovanni Jacopo, Dembowska, Kinga, Nguyen, Thao Vy Thi, Woelfle, Tim, Axfors, Cathrine, Yaldizli, Özgür, Granziera, Cristina, Kuhle, Jens, Kappos, Ludwig, & Hemkens, Lars G. (2024). Use of pragmatic randomized trials in multiple sclerosis: A systematic overview. Multiple Sclerosis Journal, 30, 463–478. https://doi.org/10.1177/13524585231221938

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial. Trials, 25. https://doi.org/10.1186/s13063-024-08454-6

Müller, Jannis, Roos, Izanne, Kalincik, Tomas, Lorscheider, Johannes, Galli, Edoardo, Benkert, Pascal, Schädelin, Sabine, Sharmin, Sifat, Einsiedler, Maximilian, Hänni, Peter, Schmid, Jürg, Kuhle, Jens, Derfuss, Tobias, Granziera, Cristina, Ziemssen, Tjalf, Siepmann, Timo, & Yaldizli, Özgür. (2024). Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis. Brain and Behavior, 14. https://doi.org/10.1002/brb3.3498

Rusche, Thilo, Yaldizli, Özgür, Galbusera, Riccardo, Mutke, Matthias, Halter, Jörg P, Lieb, Johanna, Matteazzi, Francesca, Stelmes, Anne, Bittner, Jan, Grzonka, Pascale, Frank, Nicole, Cordier, Dominik, Hench, Jürgen, Frank, Stephan, Hirsch, Hans H, Fischer, Urs, Kuhle, Jens, Sutter, Raoul, Rüegg, Stephan, & Fisch, Urs. (2024). Anti-GABA A receptor encephalitis 14 months after allogeneic haematopoietic stem-cell transplant for acute myeloid leukaemia. The Lancet, 403, 469–470. https://doi.org/10.1016/s0140-6736(23)02831-3

Cortese R., Battaglini M., Prados F., Bianchi A., Haider L., Jacob A., Palace J, Messina S., Paul F, Wuerfel J., Marignier R., Durand-Dubief F., de Medeiros Rimkus C., Callegaro D., Sato D.K., Filippi M, Rocca MA, Cacciaguerra L., Rovira A, et al. (2023). Clinical and MRI measures to identify non-acute MOG-antibody disease in adults. Brain, 146(6), 2489–2501. https://doi.org/10.1093/brain/awac480

Cerdá-Fuertes, Nuria, Nagy, Sara, Schaedelin, Sabine, Sinnecker, Tim, Ruberte, Esther, Papadopoulou, Athina, Würfel, Jens, Kuhle, Jens, Yaldizli, Özgür, Kappos, Ludwig, Derfuss, Tobias, & Décard, Bernhard F. (2023). Evaluation of frequency, severity, and independent risk factors for recurrence of disease activity after fingolimod discontinuation in a large real-world cohort of patients with multiple sclerosis. Therapeutic Advances in Neurological Disorders, 16. https://doi.org/10.1177/17562864221150312

Durrer, Alicia, Wolleb, Julia, Bieder, Florentin, Sinnecker, Tim, Weigel, Matthias, Sandkühler, Robin, Granziera, Cristina, Yaldizli, Özgür, & Cattin, Philippe C. (2023). Diffusion Models for Contrast Harmonization of Magnetic Resonance Images. 227, 526–551.

Meier, Stephanie, Willemse, Eline A.J., Schaedelin, Sabine, Oechtering, Johanna, Lorscheider, Johannes, Melie-Garcia, Lester, Cagol, Alessandro, Barakovic, Muhamed, Galbusera, Riccardo, Subramaniam, Suvitha, Barro, Christian, Abdelhak, Ahmed, Thebault, Simon, Achtnichts, Lutz, Lalive, Patrice, Müller, Stefanie, Pot, Caroline, Salmen, Anke, Disanto, Giulio, et al. (2023). Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. JAMA Neurology, 80, 287–297. https://doi.org/10.1001/jamaneurol.2022.5250

Müller, Jannis, Cagol, Alessandro, Lorscheider, Johannes, Tsagkas, Charidimos, Benkert, Pascal, Yaldizli, Özgür, Kuhle, Jens, Derfuss, Tobias, Sormani, Maria Pia, Thompson, Alan, Granziera, Cristina, & Kappos, Ludwig. (2023). Harmonizing Definitions for Progression Independent of Relapse Activity inMultiple Sclerosis A Systematic Review. JAMA Neurology, 80, 1232–1245. https://doi.org/10.1001/jamaneurol.2023.3331

Müller, Jannis, Schädelin, Sabine, Lorscheider, Johannes, Benkert, Pascal, Hänni, Peter, Schmid, Jürg, Kuhle, Jens, Derfuss, Tobias, Granziera, Cristina, & Yaldizli, Özgür. (2023). Comparative analysis of dimethyl fumarate and teriflunomide in relapsing–remitting multiple sclerosis. European Journal of Neurology, 30, 3809–3818. https://doi.org/10.1111/ene.16044

Stanikić, Mina, Braun, Julia, Ajdacic-Gross, Vladeta, Manjaly, Zina-Mary, Yaldizli, Özgür, Ineichen, Benjamin Victor, Kamm, Christian P., Iaquinto, Stefania, Gobbi, Claudio, Zecca, Chiara, Calabrese, Pasquale, & von Wyl, Viktor. (2023). Self-reports by persons with multiple sclerosis are an adequate surrogate for healthcare provider data on disease-modifying therapy and multiple sclerosis type. Multiple Sclerosis and Related Disorders, 80. https://doi.org/10.1016/j.msard.2023.105097

Etter M, Martin T, Kulsvehagen L, Pössnecker E, Duchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, et al. (2022, September 28). Severe Neuro-COVID is associated with peripheral immune signatures and signs of neurodegeneration: a prospective cross-sectional study. Sfcns.

Yaldizli Ö, & Derfuss T. (2022). All Bruton’s tyrosine kinase inhibitors have similar efficacy and risks: Commentary. (Patent No. 10). 28(10), Article 10. https://doi.org/10.1177/13524585221097562

Lisa Dinsenbacher, & Özgür Yaldizli. (2022). MS und Kinderwunsch: Was müssen Betroffene beachten? Forte, 3.

Müller, Jannis, Sinnecker, Tim, Wendebourg, Maria Janina, Schläger, Regina, Kuhle, Jens, Schädelin, Sabine, Benkert, Pascal, Derfuss, Tobias, Cattin, Philippe, Jud, Christoph, Spiess, Florian, Amann, Michael, Lincke, Therese, Barakovic, Muhamed, Cagol, Alessandro, Tsagkas, Charidimos, Parmar, Katrin, Pröbstel, Anne-Katrin, Reimann, Sophia, et al. (2022). Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder [Journal-article]. Neurology Neuroimmunology & Neuroinflammation, 9(3). https://doi.org/10.1212/nxi.0000000000001147

Müller J, Sinnecker T, Wendebourg MJ, Schläger R, Kuhle J, Schädelin S, Benkert P, Derfuss T, Cattin P, Jud C, Spiess F, Amann M, Lincke T, Barakovic M, Cagol A, Tsagkas C, Parmar K, Pröbstel AK, Reimann S, et al. (2022). Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder: A Retrospective, Cross-sectional Analysis. Neurology(R) Neuroimmunology & Neuroinflammation, 9(3). https://doi.org/10.1212/nxi.0000000000001147

Etter, M., Martins, T., Kulsvehagen, L., Pössnecker, E., Duchemin, W., Hogan, S., Sanabria-Diaz, G., Müller, J., Chiappini, A., Rychen, J., Eberhard, N., Guzman, R., MarianI, L., Keller, E., Melie-Garcia, L., Jelcic, I., Pargger, H., Siegemund, M., Kuhle, J., et al. (2022, March 8). Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-1385593/v1

Etter, M. M., A. Martins, T., Kulsvehagen, L., Pössnecker, E., Duchemin, W., Hogan, S., Sanabria-Diaz, G., Müller, J., Chiappini, A., Rychen, J., Eberhard, N., Melie-Garcia, L., Keller, E., Jelcic, I., Pargger, H., Siegemund, M., Kuhle, J., Oechtering, J., Eich, C., et al. (2022, March 2). Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and signs of neurodegeneration: a prospective cross-sectional study [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.02.18.22271039

Benkert, Pascal, Meier, Stephanie, Schaedelin, Sabine, Manouchehrinia, Ali, Yaldizli, Özgür, Maceski, Aleksandra, Oechtering, Johanna, Achtnichts, Lutz, Conen, David, Derfuss, Tobias, Lalive, Patrice H., Mueller, Christian, Müller, Stefanie, Naegelin, Yvonne, Oksenberg, Jorge R., Pot, Caroline, Salmen, Anke, Willemse, Eline, Kockum, Ingrid, et al. (2022). Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. The Lancet Neurology, 21(3), 246–257. https://doi.org/10.1016/s1474-4422(22)00009-6

Cagol, Alessandro, Schaedelin, Sabine, Barakovic, Muhamed, Benkert, Pascal, Todea, Ramona-Alexandra, Rahmanzadeh, Reza, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Melie-Garcia, Lester, Ruberte, Esther, Siebenborn, Nina, Battaglini, Marco, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Sinnecker, Tim, Lorscheider, Johannes, Fischer-Barnicol, Bettina, et al. (2022). Association of Brain Atrophy with Disease Progression Independent of Relapse Activity in Patients with Relapsing Multiple Sclerosis. JAMA Neurology, 79, 682–692. https://doi.org/10.1001/jamaneurol.2022.1025

Etter, Manina M., Martins, Tomás A., Kulsvehagen, Laila, Pössnecker, Elisabeth, Duchemin, Wandrille, Hogan, Sabrina, Sanabria-Diaz, Gretel, Müller, Jannis, Chiappini, Alessio, Rychen, Jonathan, Eberhard, Noëmi, Guzman, Raphael, Mariani, Luigi, Melie-Garcia, Lester, Keller, Emanuela, Jelcic, Ilijas, Pargger, Hans, Siegemund, Martin, Kuhle, Jens, et al. (2022). Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study. Nature Communications, 13. https://doi.org/10.1038/s41467-022-34068-0

Sinnecker, Tim, Schädelin, Sabine, Benkert, Pascal, Ruberte, Esther, Amann, Michael, Lieb, Johanna M., Naegelin, Yvonne, Müller, Jannis, Kuhle, Jens, Derfuss, Tobias, Kappos, Ludwig, Wuerfel, Jens, Granziera, Cristina, & Yaldizli, Özgür. (2022). Brain atrophy measurement over a MRI scanner change in multiple sclerosis. NeuroImage: Clinical, 36. https://doi.org/10.1016/j.nicl.2022.103148

Wolleb, Julia, Sandkühler, Robin, Bieder, Florentin, Barakovic, Muhamed, Hadjikhani, Nouchine, Papadopoulou, Athina, Yaldizli, Özgür, Kuhle, Jens, Granziera, Cristina, & Cattin, Philippe C. (2022). Learn to Ignore: Domain Adaptation for Multi-site MRI Analysis. Medical Image Computing and Computer Assisted Intervention – MICCAI 2022, 13437 LNCS, 725–735. https://doi.org/10.1007/978-3-031-16449-1_69

Sophia Reimann, Jannis Müller, Tim Sinnecker, Maria Janina Wendebourg, Regina Schlaeger, Charidimos Tsagkas, Katrin Parmar, Anne-Katrin Pröbstel, Michael Amann, Jens Würfel, Nouchine Hadjikhani, Therese Lincke, Muhamed Barakovic, Alessandro Cagol, Lester Melie-Garcia, Stephanie Meier, Aleksandra Maceski, Eline Willemse, David Leppert, et al. (2022). On the association between the choroid plexus volume and disease characteristics in multiple sclerosis. Sfcns.

Oechtering J, Schaedelin S, Benkert P, Müller S, Achtnichts L, Vehoff J, Disanto G, Findling O, Fischer-Barnicol B, Orleth A, Chan A, Pot C, Barakovic M, Rahmanzadeh R, Galbusera R, Heijnen I, Lalive PH, Wuerfel J, Subramaniam S, et al. (2021). Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis. Annals of Neurology, 90(3), 477–489. https://doi.org/10.1002/ana.26137

Allum JHJ, Rust HM, Lutz N, Schouenborg C, Fischer-Barnicol B, Haller V, Derfuss T, Kuhle J, & Yaldizli Ö. (2021). Characteristics of improvements in balance control using vibro-tactile biofeedback of trunk sway for multiple sclerosis patients. Journal of the Neurological Sciences, 425, 117432. https://doi.org/10.1016/j.jns.2021.117432

Tsagkas C, Schäfer S, Baumgartner A, Müller J, Sinnecker T, Mehling M, van der Stouwe JG, Felder S, Panagiotou A, Potlukova E, Winzeler B, Scholz MC, Timper K, Blackham K, Nickel CH, Christ-Crain M, Bingisser R, Lyrer P, Kappos L, & Yaldizli Ö. (2021). Syndrome of inappropriate antidiuretic hormone secretion and hypothalamic hypocortisolism in neuromyelitis optica. Lancet (London, England), 397(10290), 2194. https://doi.org/10.1016/s0140-6736(21)00986-7

Lorscheider J, Benkert P, Lienert C, Hänni P, Derfuss T, Kuhle J, Kappos L., & Yaldizli Ö. (2021). Comparative analysis of dimethyl fumarate and fingolimod in relapsing-remitting multiple sclerosis. Journal of Neurology, 268(3), 941–949. https://doi.org/10.1007/s00415-020-10226-6

von Wyl V, Benkert P, Moser A, Lorscheider J, Décard B, Hänni P, Lienert C, Kuhle J, Derfuss T, Kappos L, & Yaldizli Ö. (2021). Disability progression in relapse-free multiple sclerosis patients on fingolimod versus interferon-beta/glatiramer acetate. Multiple Sclerosis (Houndmills, Basingstoke, England), 27(3), 439–448. https://doi.org/10.1177/1352458520918489

Jakimovski D, Zivadinov R, Ramanthan M, Hagemeier J, Weinstock-Guttman B, Tomic D, Kropshofer H, Fuchs TA, Barro C, Leppert D, Yaldizli Ö, Kuhle J, & Benedict RH. (2020). Serum neurofilament light chain level associations with clinical and cognitive performance in multiple sclerosis: A longitudinal retrospective 5-year study. Multiple Sclerosis (Houndmills, Basingstoke, England), 26(13), 1670–1681. https://doi.org/10.1177/1352458519881428

Kronlage C, Hardmeier M, Bally S, Scholz MC, Bucher HC, Müller OK, Winterhalder C., Mongiat M, Müller J, Polymeris A, Weber M, Lausberg C, Kassi E, Kuhle J, Kappos L, Hermann W, Bernsmeier C, & Yaldizli Ö. (2020). Muscle stiffness, gait instability, and liver cirrhosis in Wilson’s disease. Lancet (London, England), 396(10256), 990. https://doi.org/10.1016/s0140-6736(20)31963-2

von Wyl V, Décard BF, Benkert P, Lorscheider J, Hänni P, Lienert C, Kuhle J, Derfuss T, Kappos L, & Yaldizli Ö. (2020). Influence of age at disease onset on future relapses and disability progression in patients with multiple sclerosis on immunomodulatory treatment. European Journal of Neurology, 27(6), 1066–1075. https://doi.org/10.1111/ene.14191

Kronlage, Cornelius, Hardmeier, Martin, Bally, Seraina, Scholz, Marleen Carina, Bucher, Heiner C, Müller, Olivia Katharina, Winterhalder, Clemens, Mongiat, Michel, Müller, Jannis, Polymeris, Alexandros, Weber, Martin, Lausberg, Christina, Kassi, Elianne, Kuhle, Jens, Kappos, Ludwig, Hermann, Wieland, Bernsmeier, Christine, & Yaldizli, Özgür. (2020). Muscle stiffness, gait instability, and liver cirrhosis in Wilson’s disease. Lancet (London, England), 396(10256), 990. https://doi.org/10.1016/s0140-6736(20)31963-2

Sander L, Horvath A, Pezold S, Andermatt S, Amann M, Sinnecker T, Wendebourg MJ, Kesenheimer E, Yaldizli Ö, Kappos L, Granziera C, Wuerfel J, Cattin P, & Schlaeger R. (2020). Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies. Frontiers in Neuroscience, 14, 609422. https://doi.org/10.3389/fnins.2020.609422

Sinnecker T, Ruberte E, Schädelin S, Canova V, Amann M, Naegelin Y, Penner IK, Müller J, Kuhle J, Décard B, Derfuss T, Kappos L, Granziera C, Wuerfel J, Magon S, & Yaldizli Ö. (2020). New and enlarging white matter lesions adjacent to the ventricle system and thalamic atrophy are independently associated with lateral ventricular enlargement in multiple sclerosis. Journal of Neurology, 267(1), 192–202. https://doi.org/10.1007/s00415-019-09565-w

Kaufmann M, Puhan MA, Kuhle J, Yaldizli Ö, Magnusson T, Kamm CP, Calabrese P, & von Wyl V. (2019). A Framework for Estimating the Burden of Chronic Diseases: Design and Application in the Context of Multiple Sclerosis. Frontiers in Neurology, 10, 953. https://doi.org/10.3389/fneur.2019.00953

Barro C, Benkert P, Disanto G, Tsagkas C, Amann M, Naegelin Y, Leppert D, Gobbi C, Granziera C, Yaldizli Ö, Michalak Z, Wuerfel J, Kappos L, Parmar K, & Kuhle J. (2018). Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis. Brain : A Journal of Neurology, 141(8), 2382–2391. https://doi.org/10.1093/brain/awy154

Lorscheider J, Benkert P, Lienert C, Hänni P, Derfuss T, Kuhle J, Kappos L, & Yaldizli Ö. (2018). Comparative analysis of natalizumab versus fingolimod as second-line treatment in relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 24(6), 777–785. https://doi.org/10.1177/1352458518768433

Miller DH, Lublin FD, Sormani MP, Kappos L, Yaldizli Ö, Freedman MS, Cree BAC, Weiner HL, Lubetzki C, Hartung HP, Montalban X, Uitdehaag BMJ, MacManus DG, Yousry TA, Gandini Wheeler-Kingshott CAM, Li B, Putzki N, Merschhemke M, Häring DA, & Wolinsky JS. (2018). Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study. Annals of Clinical and Translational Neurology, 5(3), 346–356. https://doi.org/10.1002/acn3.534

Findling O, Rust H, Yaldizli Ö, Timmermans DPH, Scheltinga A, & Allum JHJ. (2018). Balance Changes in Patients With Relapsing-Remitting Multiple Sclerosis: A Pilot Study Comparing the Dynamics of the Relapse and Remitting Phases. Frontiers in Neurology, 9, 686. https://doi.org/10.3389/fneur.2018.00686

Neuhaus M, Bagutti S, Yaldizli Ö, Zwahlen D, Schaub S, Frey B, Fischer-Barnicol B, Burgunder JM, Martory MD, Pöttgen J, Annoni JM, & Penner IK. (2018). Characterization of social cognition impairment in multiple sclerosis. European journal of neurology, 25(1), 90–96. https://doi.org/10.1111/ene.13457

Ruberte E, Sinnecker T, Amann M, Gaetano L, Naegelin Y, Penner IK, Kuhle J, Derfuss T, Kappos L, Granziera C, Wuerfel J, & Yaldizli Ö. (2018). Central Slab versus Whole Brain to Measure Brain Atrophy in Multiple Sclerosis. European Neurology, 80(3-4), 207–214. https://doi.org/10.1159/000495798

Yaldizli Ö, Sethi V, Pardini M, Tur C, Mok KY, Muhlert N, Liu Z, Samson RS, Wheeler-Kingshott CAM, Yousry TA, Houlden H, Hardy J, Miller DH, & Chard DT. (2018). Response to the commentary of Yates RL and DeLuca GC on the study: HLA-DRB1*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis. 19, 168–170. https://doi.org/10.1016/j.msard.2016.08.006

Barro, C., Benkert, P., Grobke, S., Naegelin, Y., Disanto, G., Amann, M., Magon, S., Derfuss, T., Yaldizli, O., Parmar, K., Wuerfel, J., Kappos, L., & Kuhle, J. (2017). Serum neurofilament light chain correlates with disease activity and predicts clinical and MRI outcomes in MS. 23, 297–298. SAGE PUBLICATIONS LTD.

Lorscheider, J., Benkert, P., Lienert, C., Hanni, P., Schmid, J., Derfuss, T., Kuhle, J., Kappos, L., & Yaldizli, O. (2017). Fingolimod vs. dimethyl fumarate in relapsing-remitting multiple sclerosis: propensity score matched comparison in a large observational data set. 23, 601–602. SAGE PUBLICATIONS LTD.

Sinnecker, T., Ruberte, E., Amann, M., Naegelin, Y., Radue, E. W., Penner, I. K., Kuhle, J., Derfuss, T., Stippich, C., Kappos, L., Wuerfel, J., & Yaldizli, O. (2017). Comparison between central and whole brain atrophy in multiple sclerosis measured by structural image evaluation using normalization of atrophy (SIENA). 23, 389. SAGE PUBLICATIONS LTD.

D’Souza M, Yaldizli Ö, John R, Vogt DR, Papadopoulou A, Lucassen E, Menegola M, Andelova M, Dahlke F, Schnyder F, & Kappos L. (2017). Neurostatus e-Scoring improves consistency of Expanded Disability Status Scale assessments: A proof of concept study. Multiple Sclerosis (Houndmills, Basingstoke, England), 23(4), 597–603. https://doi.org/10.1177/1352458516657439

Kuhle J, Nourbakhsh B, Grant D, Morant S, Barro C, Yaldizli Ö, Pelletier D, Giovannoni G, Waubant E, & Gnanapavan S. (2017). Serum neurofilament is associated with progression of brain atrophy and disability in early MS. Neurology, 88(9), 826–831. https://doi.org/10.1212/wnl.0000000000003653

Pardini, M, Botzkowski, D, Müller, S, Vehoff, J, Kuhle, J, Ruberte, E, Würfel, J, Gass, A, Valmaggia, C, Tettenborn, B, Putzki, N, & Yaldizli, Ö. (2016). The association between retinal nerve fibre layer thickness and N-acetyl aspartate levels in multiple sclerosis brain normal-appearing white matter: a longitudinal study using magnetic resonance spectroscopy and optical coherence tomography. EUROPEAN JOURNAL OF NEUROLOGY, 23, 1769–1774. https://doi.org/10.1111/ene.13116

Pardini M, Sudre CH, Prados F, Yaldizli Ö, Sethi V, Muhlert N, Samson RS, van de Pavert SH, Cardoso MJ, Ourselin S, Gandini Wheeler-Kingshott CA, Miller DH, & Chard DT. (2016). Relationship of grey and white matter abnormalities with distance from the surface of the brain in multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry, 87(11), 1212–1217. https://doi.org/10.1136/jnnp-2016-313979

Barro, C., Derfuss, T., Nagelin, Y., Benkert, P., Schadelin, S., Yaldizli, O., Achtnichts, L., Nedeltchev, K., Kamm, C. P., Salmen, A., Lalive, P. H., Schluep, M., Du Pasquier, R., Muller, S., Vehoff, J., Norgren, N., Zecca, C., Disanto, G., Gobbi, C., et al. (2016). High sensitivity serum neurofilament-light chain measurements correlate with disease activity and disability in multiple sclerosis and are reduced after immunomodulatory treatment intervention. 22, 843–844. SAGE PUBLICATIONS LTD.

Lienert, C., Benkert, P., Beer, S., Hanni, P., Pardini, M., D’Souza, M., Derfuss, T., Kuhle, J., Kappos, L., & Yaldizli, O. (2016). Lower relapse rates with natalizumab as compared with fingolimod as second-line treatment in relapsing-remitting multiple sclerosis. 22, 627. SAGE PUBLICATIONS LTD.

Ruberte, E., Amann, M., Naegelin, Y., Penner, I. K., Pardini, M., Kuhle, J., Derfuss, T., Stippich, C., Kappos, L., Wuerfel, J., & Yaldizli, O. (2016). Lateral Ventricle Volume change is associated with neurological and cognitive disability in multiple sclerosis: a 5-years follow-up study using an automated lateral ventricle segmentation algorithm. 22, 556–557. SAGE PUBLICATIONS LTD.

Ruberte, E., Amann, M., Naegelin, Y., Penner, I. K., Pardini, M., Kuhle, J., Derfuss, T., Stippich, C., Kappos, L., Wuerfel, J., & Yaldizli, O. (2016). Validation of an automated lateral ventricle delineation algorithm (ALVIN) in multiple sclerosis. 22, 557–558. SAGE PUBLICATIONS LTD.

van de Pavert, S. H., Pardini, M., Eshaghi, A., Prados, F., Yaldizli, O., Sethi, V., Ourselin, S., Wheeler-Kingshott, C. A. Gandini, Miller, D. H., Ciccarelli, O., & Chard, D. T. (2016). Spatial and temporal characteristics of magnetisation transfer ratio changes in different corticothalamic systems in multiple sclerosis. 22, 519–520. SAGE PUBLICATIONS LTD.

van der Logt RP, Findling O, Rust H, Yaldizli O, & Allum JH. (2016). The effect of vibrotactile biofeedback of trunk sway on balance control in multiple sclerosis. Multiple Sclerosis and Related Disorders, 8, 58–63. https://doi.org/10.1016/j.msard.2016.05.003

Yaldizli Ö, Sethi V, Pardini M, Tur C, Mok KY, Muhlert N, Liu Z, Samson RS, Wheeler-Kingshott CA, Yousry TA, Houlden H, Hardy J, Miller DH, & Chard DT. (2016). HLA-DRB*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis. Multiple sclerosis and related disorders, 7, 47–52. https://doi.org/10.1016/j.msard.2016.03.003

Datta, Gourab, Battaglini, Marco, Scott, Gregory, Yaldizli, Ozgur, Santos-Ribeiro, Andre, Rabiner, Eugenii, Gunn, Roger, Owen, David, Malik, Omar, Ciccarelli, Olga, Nicholas, Richard, Langdon, Dawn, De Stefano, Nicola, & Matthews, Paul. (2016). Cortical [11C]PBR28 PET Measures of Microglial Inflammation Explain Differences in Cognitive Performance of People with MS. NEUROLOGY, 86.

Yaldizli Ö, Penner I.-K., Yonekawa T, Naegelin Y, Kuhle J, Pardini M., Chard DT, Stippich C, Kira JI, Bendfeldt K., Amann M., Radue EW, Kappos L, & Sprenger T. (2016). The association between olfactory bulb volume, cognitive dysfunction, physical disability and depression in multiple sclerosis. European Journal of Neurology, 23(3), 510–519. https://doi.org/10.1111/ene.12891

Yaldizli Ö, Pardini M, Sethi V, Muhlert N, Liu Z, Tozer DJ, Samson RS, Wheeler-Kingshott CA, Yousry TA, Miller DH, & Chard DT. (2016). Characteristics of lesional and extra-lesional cortical grey matter in relapsing-remitting and secondary progressive multiple sclerosis: A magnetisation transfer and diffusion tensor imaging study. Multiple sclerosis (Houndmills, Basingstoke, England), 22(2), 150–159. https://doi.org/10.1177/1352458515586085

Callegari I, Mattei C, Benassi F, Krueger F, Grafman J, Yaldizli Ö, Sassos D, Massucco D, Scialò C, Nobili F, Serrati C, Amore M, Cocito L, Emberti Gialloreti L, & Pardini M. (2016). Agomelatine Improves Apathy in Frontotemporal Dementia. Neuro-degenerative diseases, 16(5-6), 352–356. https://doi.org/10.1159/000445873

Disanto, G., Benkert, P., Lorscheider, J., Mueller, S., Vehoff, J., Zecca, C., Ramseier, S., Achtnichts, L., Findling, O., Nedeltchev, K., Radue, E. W., Sprenger, T., Stippich, C., Derfuss, T., Louvion, J. F., Kamm, C. P., Mattle, H. P., Lotter, C., Du Pasquier, R., et al. (2016). The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options. PLoS One, 11(3), e0152347. https://doi.org/10.1371/journal.pone.0152347

Kuhle, Jens, Barro, Christian, Disanto, Giulio, Mathias, Amandine, Soneson, Charlotte, Bonnier, Guillaume, Yaldizli, Ozgür, Regeniter, Axel, Derfuss, Tobias, Canales, Mathieu, Schluep, Myriam, Du Pasquier, Renaud A., Krueger, Gunnar, & Granziera, Cristina. (2016). Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity. Multiple Sclerosis Journal, 22(12), 1550–1559. https://doi.org/10.1177/1352458515623365

Pardini M, Cordano C, Guida S, Grafman J, Krueger F, Sassos D, Massucco D, Abate L, Yaldizli Ö, Serrati C, Amore M, Mattei C, Cocito L, & Emberti Gialloreti L. (2016). Prevalence and cognitive underpinnings of isolated apathy in young healthy subjects. Journal of affective disorders, 189, 272–275. https://doi.org/10.1016/j.jad.2015.09.062

Pardini M, Yaldizli Ö, Sethi V, Muhlert N, Liu Z, Samson RS, Altmann DR, Ron MA, Wheeler-Kingshott CA, Miller DH, & Chard DT. (2015). Motor network efficiency and disability in multiple sclerosis. Neurology, 85(13), 1115–1122. https://doi.org/10.1212/wnl.0000000000001970

Liu Z, Pardini M, Yaldizli Ö, Sethi V, Muhlert N, Wheeler-Kingshott CA, Samson RS, Miller DH, & Chard DT. (2015). Magnetization transfer ratio measures in normal-appearing white matter show periventricular gradient abnormalities in multiple sclerosis. Brain : a journal of neurology, 138(Pt 5), 1239–1246. https://doi.org/10.1093/brain/awv065

Kuhle, J., Disanto, G., Dobson, R., Adiutori, R., Bianchi, L., Topping, J., Bestwick, J. P., Meier, U. C., Marta, M., Dalla Costa, G., Runia, T., Evdoshenko, E., Lazareva, N., Thouvenot, E., Iaffaldano, P., Direnzo, V., Khademi, M., Piehl, F., Comabella, M., et al. (2015). Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study. Multiple Sclerosis Journal, 21(8), 1013–1024. https://doi.org/10.1177/1352458514568827

Liu Z, Yaldizli Ö, Pardini M, Sethi V, Kearney H, Muhlert N, Wheeler-Kingshott C, Miller DH, & Chard DT. (2015). Cervical cord area measurement using volumetric brain magnetic resonance imaging in multiple sclerosis. Multiple sclerosis and related disorders, 4(1), 52–57. https://doi.org/10.1016/j.msard.2014.11.004

Chard,DT, Liu,Z, Pardini,M, Yaldizli,O, Sethi,V, Muhlert,N, Wheeler-Kingshott,CAM, Samson,RS, & Miller,DH. (2015). Association of Multiple Sclerosis Normal Appearing White Matter Abnormality with Periventricular Location and Secondary Progression. Annual Meeting American Academy of Neurology, P6.

Pardini,M, Yaldizli,O, Sethi,V, Muhlert,N, Liu,Z, Samson,RS, Altmann,DR, Ron,MA, Wheeler-Kingshott,CAM, Miller,DHM, & Chard,DT. (2015). The relationship of a multi-parameter MRI measure of motor network efficiency with disability in multiple sclerosis. Annual Meeting American Academy of Neurology, P6.

Yaldizli,O, Pardini,M, Sethi,V, Muhlert,N, Liu,Z, Tozer,DJ, Samson,RS, Wheeler-Kingshott,CAM, Yousry,TA, Miller,DH, & Chard,DT. (2015). Diffusion Tensor Imaging Abnormalities in Multiple Sclerosis Cortical Lesions and Normal-Appearing Grey Matter and their Associations with Disability. Annual Meeting American Academy of Neurology, P6.

Flachenecker P, Buckow K, Pugliatti M, Kes VB, Battaglia MA, Boyko A, Confavreux C, Ellenberger D, Eskic D, Ford D, Friede T, Fuge J, Glaser A, Hillert J, Holloway E, Ioannidou E, Kappos L, Kasilingam E, Koch-Henriksen N, et al. (2014). Multiple sclerosis registries in Europe - results of a systematic survey. Multiple sclerosis (Houndmills, Basingstoke, England), 20(11), 1523–1532. https://doi.org/10.1177/1352458514528760

Pardini M, Uccelli A, Grafman J, Yaldizli Ö, Mancardi G, & Roccatagliata L. (2014). Isolated cognitive relapses in multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry, 85(9), 1035–1037. https://doi.org/10.1136/jnnp-2013-307275

Papadopoulou A, Naegelin Y, Weier K, Amann M, Hirsch J, von Felten S, Yaldizli O, Sprenger T, Radue EW, Kappos L, & Gass A. (2014). MRI characteristics of periaqueductal lesions in multiple sclerosis. Multiple Sclerosis and Related Disorders, 3(4), 542–551. https://doi.org/10.1016/j.msard.2014.01.001

Papadopoulou, A., Menegola, M., Kuhle, J., Ramagopalan, S. V., D’Souza, M., Sprenger, T., Radue, E. W., Kappos, L., & Yaldizli, O. (2014). Lesion-to-ventricle distance and other risk factors for the persistence of newly formed black holes in relapsing-remitting multiple sclerosis. Multiple Sclerosis Journal, 20(3), 322–330. https://doi.org/10.1177/1352458513495583

Yaldizli, O., Penner, I. K., Frontzek, K., Naegelin, Y., Amann, M., Papadopoulou, A., Sprenger, T., Kuhle, J., Calabrese, P., Radu, E. W., Kappos, L., & Gass, A. (2014). The relationship between total and regional corpus callosum atrophy, cognitive impairment and fatigue in multiple sclerosis patients. Multiple Sclerosis Journal, 20(3), 356–364. https://doi.org/10.1177/1352458513496880

Pardini,M, Sethi,V, Muhlert,N, Yaldizli,O, Palesi,F, Altmann,D, Ron,M, Wheeler-Kingshott,CAM, Miller,DH, & Chard,DT. (2014). Network Efficiency As A Final Common Pathway For Cognitive Deficits In Multiple Sclerosis: A Single Network Graph Theory Study. Annual Meeting American Academy of Neurology, P6.

Corporaal, Sharissa H A, Gensicke, Henrik, Kuhle, Jens, Kappos, Ludwig, Allum, John H J, & Yaldizli, Özgür. (2013). Balance control in multiple sclerosis : correlations of trunk sway during stance and gait tests with disease severity. Gait & Posture, 37(1), 55–60. https://doi.org/10.1016/j.gaitpost.2012.05.025

Hafner P, Yaldizli O, & Baumann T. (2013). Schwindel aus neurologischer Sicht unter spezieller Berücksichtigung von Notfallsituationen. Therapeutische Umschau. Revue Therapeutique, 70(1), 12–14. https://doi.org/10.1024/0040-5930/a000356

Kuhle, J, Malmeström, C, Axelsson, M, Plattner, K, Yaldizli, O, Derfuss, T, Giovannoni, G, Kappos, L, & Lycke, J. (2013). Neurofilament light and heavy subunits compared as therapeutic biomarkers in multiple sclerosis. Acta Neurologica Scandinavica, 128(6), e33–6. https://doi.org/10.1111/ane.12151

van Dijk, Jitse P., Havlikova, Eva, Rosenberger, Jaroslav, Nagyova, Iveta, Skorvanek, Matej, Gdovinova, Zuzana, Lok, Willem, Groothoff, Johan W., & Middel, Berrie. (2013). Influence of Disease Severity on Fatigue in Patients with Parkinson’s Disease Is Mainly Mediated by Symptoms of Depression. EUROPEAN NEUROLOGY, 70, 201–209. https://doi.org/10.1159/000351779

Yaldizli O., Kuhle J., Derfuss T., Sprenger T., & Kappos L. (2013). Neurologist-in-training: Multiple sclerosis. Schweizer Archiv Fur Neurologie Und Psychiatrie, 164(1), 37–40. https://doi.org/10.4414/sanp.2013.00103

Hafner,Patricia, Yaldizli,Özgür, & Baumann,Thomas. (2013). Schwindel aus neurologischer Sicht unter spezieller Berücksichtigung von Notfallsituationen. Ther Umsch, 70(3), 12–14.

Yaldizli,O, Kuhle,J, Derfuss,T, Sprenger,T, & Kappos,L. (2013). Resident corner 2012: Multiple sclerosis. Schweizer Archiv Für Neurologie Und Psychiatrie, 164(4), 37–40.

Zwahlen,D, Schaub,S, Yaldizli,O, Opwis,K, Annoni,JM, Kappos,L, & Penner,IK. (2013). Theory of mind deficits in patients with multiple sclerosis – a separate entity of socio-cognitive impairment? ECTRIMS 2013, 990.

Fanchamps, Malou H J, Gensicke, Henrik, Kuhle, Jens, Kappos, Ludwig, Allum, John H J, & Yaldizli, Ozgür. (2012). Screening for balance disorders in mildly affected multiple sclerosis patients. Journal of Neurology, 259(7), 1413–1419. https://doi.org/10.1007/s00415-011-6366-5

Gensicke, H., Leppert, D., Yaldizli, O., Lindberg, R. L., Mehling, M., Kappos, L., & Kuhle, J. (2012). Monoclonal Antibodies and Recombinant Immunoglobulins for the Treatment of Multiple Sclerosis. CNS Drugs, 26(1), 11–37. https://doi.org/10.2165/11596920-000000000-00000

Lienert,C, Schoetzau,A, Beer,S, Kappos,L, & Yaldizli,O. (2012). Immunomodulatory treatment of multiple sclerosis in Switzerland – a nationwide follow-up of 8046 patients. ECTRIMS 2012, 213.

Yaldizli,O. (2012). Immunmodulierende Basistherapie nach dem ersten Schub einer möglichen Multiple Sklerose (Vol. 4, pp. 58–62).

Yonekawa,T, Penner,IK, Naegelin,Y, Kuhle,J, Stippich,C, Radue,EWR, Kappos,L, Sprenger,T, & Yaldizli,O. (2012). Olfactory bulb volume and neuropsychological performance, fatigue severity and depression in multiple sclerosis patients. ECTRIMS 2012, 378.

Yaldizli Ö, Glassl S, Sturm D, Papadopoulou A, Gass A, Tettenborn B, & Putzki N. (2011). Fatigue and progression of corpus callosum atrophy in multiple sclerosis. Journal of neurology, 258(12), 2199–2205. https://doi.org/10.1007/s00415-011-6091-0

Kuhle, Jens, Gosert, Rainer, Buhler, R., Derfuss, Tobias, Sutter, R, Yaldizli, Ozgür, Radue, E. W., Ryschkewitsch, C., Major, E. O., Kappos, Ludwig, Frank, Stephan, & Hirsch, Hans H. (2011). Management and outcome of CSF-JC virus PCR-negative PML in a natalizumab-treated patient with MS. Neurology, 77(23), 2010–2016. https://doi.org/10.1212/wnl.0b013e31823b9b27

Yaldizli O., Kuhle,J, Derfuss T., Sprenger T., & Kappos,L. (2011). Neurologist-in-training. Schweizer Archiv Fur Neurologie Und Psychiatrie, 162(4), 171–173. https://doi.org/10.4414/sanp.2011.02270

Yaldizli,O, Kuhle,J, Derfuss,T, Sprenger,T, & Kappos,L. (2011). Resident corner 2011: Multiple sclerosis. Schweizer Archiv Für Neurologie Und Psychiatrie, 162(3), 171–173.