Prof. Dr. Henriette Meyer zu Schwabedissen

Kinzi, Jonny, Grube, Markus, Seibert, Isabell, Siegmund, Werner, & Meyer zu Schwabedissen, Henriette E. (2024). Increased coproporphyrin serum levels in healthy volunteers treated with the cholesterol uptake inhibitor ezetimibe [Journal-article]. Clinical and Translational Science, 17(10). https://doi.org/10.1111/cts.70041

Stäuble, Céline K., Lampert, Markus L., Allemann, Samuel S., & Meyer zu Schwabedissen, Henriette E. (2024). A Clinical Practice Perspective on the Evaluation of OATP1B1‐associated Drug Interactions [Journal-article]. Clinical Pharmacology & Therapeutics. https://doi.org/10.1002/cpt.3247

Rysz, Marta, Schäfer, Anima M., Paloumpis, Nikolaos, Kinzi, Jonny, Brecht, Karin, Seibert, Isabell, Schmidlin, Seraina, In-Albon, Katja, Ricklin, Daniel, & Meyer zu Schwabedissen, Henriette E. (2024). Humanization of SLCO2B1 in Rats Increases rCYP3A1 Protein Expression but Not the Metabolism of Erlotinib to OSI-420 [Journal-article]. Journal of Pharmacology and Experimental Therapeutics, 389(1), 87–95. https://doi.org/10.1124/jpet.123.001884

Tilen, Romy, Berger, Christoph, Allemann, Samuel, & Meyer zu Schwabedissen, Henriette. (2024). Information in summaries of product characteristics about use in children is limited and needs standardisation: a systematic analysis in Switzerland [Journal-article]. Archives of Disease in Childhood, archdischild–archdisc2023. https://doi.org/10.1136/archdischild-2023-325611

Kinzi, J., Hussner, J., Schäfer, A. M., Treyer, A., Seibert, I., Tillmann, A., Mueller, V., Gherardi, C., Vonwyl, C., Hamburger, M., & Meyer zu Schwabedissen, H. E. (2024). Influence of Slco2b1-knockout and SLCO2B1-humanization on coproporphyrin I and III levels in rats. British Journal of Pharmacology, 181(1), 36–53. https://doi.org/10.1111/bph.16205

Schäfer, Anima M., Rysz, Marta A., Schädeli, Julia, Hübscher, Michelle, Khosravi, Haleh, Fehr, Michelle, Seibert, Isabell, Potterat, Olivier, Smieško, Martin, & Meyer zu Schwabedissen, Henriette E. (2024). St. John’s Wort Formulations Induce Rat CYP3A23-3A1 Independent of Their Hyperforin Content [Journal-article]. Molecular Pharmacology, 105, 14–22. https://doi.org/10.1124/molpharm.123.000725

Wiss, Florine M., Allemann, Samuel S., Meyer zu Schwabedissen, Henriette E., Stäuble, Céline K., Mikoteit, Thorsten, & Lampert, Markus L. (2024). Recurrent high creatine kinase levels under clozapine treatment - a case report assessing a suspected adverse drug reaction [Journal-article]. Frontiers in Psychiatry, 15. https://doi.org/10.3389/fpsyt.2024.1397876

Kinzi, J., Grube, M., Brecht, K., Seibert, I., Siegmund, W., & Meyer zu Schwabedissen, H. E. (2023). Various effects of repeated rifampin dosing on coproporphyrin levels in humans. Clinical and Translational Science, 16(11), 2289–2298. https://doi.org/10.1111/cts.13629

Kinzi, J., Grube, M., Hussner, J., Seibert, I., Hamburger, M., & Meyer zu Schwabedissen, H. E. (2023). The influence of OATP2B1 and atorvastatin on coproporphyrin isomers in rats. Journal of Pharmacological Sciences, 153(3), 170–174. https://doi.org/10.1016/j.jphs.2023.09.003

Bollinger, A., Jeiziner, C., Meyer Zu Schwabedissen, H. E., Hersberger, K. E., Allemann, S. S., & Stäuble, C. K. (2023). Severe systemic adverse reactions to ophthalmic timolol in a CYP2D6 homozygous *4 allele carrier: a case report. Pharmacogenomics, 24, 739–746. https://doi.org/10.2217/pgs-2023-0122

Bollinger, Anna, Stäuble, Céline K, Jeiziner, Chiara, Wiss, Florine M, Hersberger, Kurt E, Lampert, Markus L, Meyer Zu Schwabedissen, Henriette E, & Allemann, Samuel S. (2023). Genotyping of Patients with Adverse Drug Reaction or Therapy Failure: Database Analysis of a Pharmacogenetics Case Series Study. Pharmacogenomics and Personalized Medicine, 16, 693–706. https://doi.org/10.2147/pgpm.s415259

Jeiziner, Chiara, Meyer Zu Schwabedissen, Henriette E, Hersberger, Kurt E, & Allemann, Samuel S. (2023). Pharmacogenetic testing and counselling in the community pharmacy: mixed-methods study of a new pharmacist-led service. International Journal of Clinical Pharmacy, https: https://doi.org/10.1007/s11096-023-01596-8

Kirchner, Kevin, Garvert, Linda, Wittfeld, Katharina, Ameling, Sabine, Bülow, Robin, Meyer Zu Schwabedissen, Henriette, Nauck, Matthias, Völzke, Henry, Grabe, Hans J, & Van der Auwera, Sandra. (2023). Deciphering the Effect of Different Genetic Variants on Hippocampal Subfield Volumes in the General Population. International Journal of Molecular Sciences, 24(2), 1120. https://doi.org/10.3390/ijms24021120

Rysz, Marta A., Kinzi, Jonny, Schäfer, Anima M., In-Albon, Katja, Zürcher, Simone, Schmidlin, Seraina, Seibert, Isabell, Schwardt, Oliver, Ricklin, Daniel, & Meyer zu Schwabedissen, Henriette E. (2023). Simultaneous quantification of atorvastatin, erlotinib and OSI-420 in rat serum and liver microsomes using a novel liquid chromatography-mass spectrometry method. Journal of Pharmaceutical and Biomedical Analysis, 236. https://doi.org/10.1016/j.jpba.2023.115716

Wiss, Florine M, Stäuble, Céline K, Meyer Zu Schwabedissen, Henriette E, Allemann, Samuel S, & Lampert, Markus L. (2023). Pharmacogenetic Analysis Enables Optimization of Pain Therapy: A Case Report of Ineffective Oxycodone Therapy. Journal of Personalized Medicine, 13(5), 829. https://doi.org/10.3390/jpm13050829

Brouwer, Kim L R, Evers, Raymond, Hayden, Elizabeth, Hu, Shuiying, Li, Cindy Yanfei, Meyer Zu Schwabedissen, Henriette E, Neuhoff, Sibylle, Oswald, Stefan, Piquette-Miller, Micheline, Saran, Chitra, Sjöstedt, Noora, Sprowl, Jason A, Stahl, Simone H, & Yue, Wei. (2022). Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium. Clinical Pharmacology and Therapeutics, 112(3), 461–484. https://doi.org/10.1002/cpt.2605

Huynh, Christine, Seeland, Swen, Segrestaa, Jerome, Gnerre, Carmela, Hogeback, Jens, Meyer Zu Schwabedissen, Henriette E, Dingemanse, Jasper, & Sidharta, Patricia N. (2022). Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist:; In Vitro; , Preclinical, and Clinical Data. Frontiers in Pharmacology, 13, 812065. https://doi.org/10.3389/fphar.2022.812065

Jeiziner, Chiara, Allemann, Samuel S, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2022). Is Pharmacogenetic Panel Testing Applicable to Low-Dose Methotrexate in Rheumatoid Arthritis? - A Case Report. Pharmacogenomics and Personalized Medicine, 15, 465–475. https://doi.org/10.2147/pgpm.s354011

Mettler, Lina G, Brecht, Karin, Butterweck, Veronika, & Meyer Zu Schwabedissen, Henriette E. (2022). Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 148, 112698. https://doi.org/10.1016/j.biopha.2022.112698

Schäfer, Anima M, Gilgen, Pierrine M, Spirgi, Clara, Potterat, Olivier, & Meyer Zu Schwabedissen, Henriette E. (2022). Constituents of Passiflora incarnata, but Not of Valeriana officinalis, Interact with the Organic Anion Transporting Polypeptides (OATP)2B1 and OATP1A2. Planta Medica, 88(2), 152–162. https://doi.org/10.1055/a-1305-3936

Stäuble, Céline K., Jeiziner, Chiara, Bollinger, Anna, Wiss, Florine M., Hatzinger, Martin, Hersberger, Kurt E., Ihde, Thomas, Lampert, Markus L., Mikoteit, Thorsten, Meyer Zu Schwabedissen, Henriette E., & Allemann, Samuel S. (2022). A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting. Pharmacy (Basel, Switzerland), 10(4), 86. https://doi.org/10.3390/pharmacy10040086

Stäuble, Céline K, Meier, Rebecca, Lampert, Markus L, Mikoteit, Thorsten, Hatzinger, Martin, Allemann, Samuel S, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2022). Case report: Non-response to fluoxetine in a homozygous 5-HTTLPR S-allele carrier of the serotonin transporter gene. Frontiers in Psychiatry, 13, 942268. https://doi.org/10.3389/fpsyt.2022.942268

Taggi, Valerio, Riera Romo, Mario, Piquette-Miller, Micheline, Meyer Zu Schwabedissen, Henriette E, & Neuhoff, Sibylle. (2022). Transporter Regulation in Critical Protective Barriers: Focus on Brain and Placenta. Pharmaceutics, 14(7), 1376. https://doi.org/10.3390/pharmaceutics14071376

Tilen, Romy, Paioni, Paolo, Goetschi, Aljoscha N, Goers, Roland, Seibert, Isabell, Müller, Daniel, Bielicki, Julia A, Berger, Christoph, Krämer, Stefanie D, & Meyer Zu Schwabedissen, Henriette E. (2022). Pharmacogenetic Analysis of Voriconazole Treatment in Children. Pharmaceutics, 14(6), 1289. https://doi.org/10.3390/pharmaceutics14061289

Tilen, Romy, Panis, Dalibor, Aeschbacher, Samuel, Sabine, Thomas, Meyer Zu Schwabedissen, Henriette E, & Berger, Christoph. (2022). Development of the Swiss Database for dosing medicinal products in pediatrics. European Journal of Pediatrics, 181((3)), 1221–1231. https://doi.org/10.1007/s00431-021-04304-8

Wittwer, Nina L, Meier, Christoph R, Huber, Carola A, Meyer Zu Schwabedissen, Henriette E, Allemann, Samuel, & Schneider, Cornelia. (2022). Utilization of Drugs with Pharmacogenetic Dosing Recommendations in Switzerland: A Descriptive Study Using the Helsana Database. Pharmacogenomics and Personalized Medicine, 15, 967–976. https://doi.org/10.2147/pgpm.s382214

Bachmann, Fabio, Duthaler, Urs, Meyer Zu Schwabedissen, Henriette E., Puchkov, Maxim, Huwyler, Jörg, Haschke, Manuel, & Krähenbühl, Stephan. (2021). Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2. Clinical Pharmacology and Therapeutics, 109(6), 1505–1516. https://doi.org/10.1002/cpt.2141

Bezençon, Jacqueline, Saran, Chitra, Hussner, Janine, Beaudoin, James J, Zhang, Yueping, Shen, Hong, Fallon, John K, Smith, Philip C, Meyer zu Schwabedissen, Henriette E, & Brouwer, Kim L R. (2021). Endogenous Coproporphyrin I and III are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR; -; ) Rats. Journal of Pharmaceutical Sciences, S0022-3549(20), 30607–30609. https://doi.org/10.1016/j.xphs.2020.10.017

Goers, Roland, Coman Schmid, Diana, Jäggi, Vera F, Paioni, Paolo, Okoniewski, Michal J, Parker, Althea, Bangerter, Beat, Georgakopoulou, Sofia, Sengstag, Thierry, Bielicki, Julia, Tilen, Romy, Vermeul, Swen, Krämer, Stefanie D, Berger, Christoph, Rinn, Bernd, & Meyer Zu Schwabedissen, Henriette E. (2021). SwissPK; cdw; - A clinical data warehouse for the optimization of pediatric dosing regimens. CPT: Pharmacometrics & Systems Pharmacology, 1578–1587. https://doi.org/10.1002/psp4.12723

Hussner, Janine, Foletti, Annalise, Seibert, Isabell, Fuchs, Anja, Schuler, Eveline, Malagnino, Vanessa, Grube, Markus, & Meyer Zu Schwabedissen, Henriette E. (2021). Differences in transport function of the human and rat orthologue of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1). Drug Metabolism and Pharmacokinetics, 41, 100418. https://doi.org/10.1016/j.dmpk.2021.100418

Huynh, Christine, Brussee, Janneke M, Pouzol, Laetitia, Fonseca, Marlene, Meyer Zu Schwabedissen, Henriette E, Dingemanse, Jasper, & Sidharta, Patricia N. (2021). Target engagement of the first-in-class CXCR7 antagonist ACT-1004-1239 following multiple-dose administration in mice and humans. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 144, 112363. https://doi.org/10.1016/j.biopha.2021.112363

Huynh, Christine, Henrich, Andrea, Strasser, Daniel S., Boof, Marie-Laure, Al-Ibrahim, Mohamed, Meyer Zu Schwabedissen, Henriette E., Dingemanse, Jasper, & Ufer, Mike. (2021). A Multipurpose First-in-Human Study With the Novel CXCR7 Antagonist ACT-1004-1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker. Clinical Pharmacology and Therapeutics, 109(6), 1648–1659. https://doi.org/10.1002/cpt.2154

Jeiziner, Chiara, Stäuble, Céline K, Lampert, Markus L, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2021). Enriching Medication Review with a Pharmacogenetic Profile - A Case of Tamoxifen Adverse Drug Reactions. Pharmacogenomics and Personalized Medicine, 14, 279–286. https://doi.org/10.2147/pgpm.s285807

Jeiziner, Chiara, Stäuble, Céline K, Lampert, Markus L, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2021). Enriching Medication Review with a Pharmacogenetic Profile - A Case of Tamoxifen Adverse Drug Reactions. Pharmacogenomics and Personalized Medicine, 14, 279–286. https://doi.org/10.2147/pgpm.s285807

Jeiziner, Chiara, Wernli, Ursina, Suter, Katja, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2021). HLA-associated adverse drug reactions - scoping review. Clinical and Translational Science, 1648–1658. https://doi.org/10.1111/cts.13062

Jeiziner, C., Suter, K., Wernli, U., Barbarino, J. M., Gong, L., Whirl-Carrillo, M., Klein, T. E., Szucs, T. D., Hersberger, K. E., & Meyer Zu Schwabedissen, H. E. (2021). Pharmacogenetic information in Swiss drug labels - a systematic analysis. Pharmacogenomics Journal, 21(4), 423–434. https://doi.org/10.1038/s41397-020-00195-4

Kinzi, Jonny, Grube, Markus, & Meyer Zu Schwabedissen, Henriette E. (2021). OATP2B1 - The underrated member of the organic anion transporting polypeptide family of drug transporters? Biochemical Pharmacology, 188, 114534. https://doi.org/10.1016/j.bcp.2021.114534

Meyer zu Schwabedissen, Henriette, & Schäfer, Anima. (2021). Johanniskraut - Neue Erkenntnisse zum Wirkmechanismus. Phytokompass, 3, 24–27.

Paioni, Paolo, Jäggi, Vera F, Tilen, Romy, Seiler, Michelle, Baumann, Philipp, Bräm, Dominic S, Jetzer, Carole, Haid, Robin T U, Goetschi, Aljoscha N, Goers, Roland, Müller, Daniel, Coman Schmid, Diana, Meyer Zu Schwabedissen, Henriette E, Rinn, Bernd, Berger, Christoph, & Krämer, Stefanie D. (2021). Gentamicin Population Pharmacokinetics in Pediatric Patients-A Prospective Study with Data Analysis Using the saemix Package in R. Pharmaceutics, 13(10), 1596. https://doi.org/10.3390/pharmaceutics13101596

Schäfer, Anima M., Meyer Zu Schwabedissen, Henriette E., & Grube, Markus. (2021). Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications. Pharmaceutics, 13(6), 834. https://doi.org/10.3390/pharmaceutics13060834

Stäuble, Céline K, Jeiziner, Chiara, Hersberger, Kurt E, Meyer zu Schwabedissen, Henriette E, & Lampert, Markus L. (2021). Pharmacogenetics in Pharmaceutical Care-Piloting an Application-Oriented Blended Learning Concept. Pharmacy (Basel, Switzerland), 9(3), 152. https://doi.org/10.3390/pharmacy9030152

Stäuble, Céline K, Lampert, Markus L, Allemann, Samuel, Hatzinger, Martin, Hersberger, Kurt E, Meyer Zu Schwabedissen, Henriette E, Imboden, Christian, & Mikoteit, Thorsten. (2021). Pharmacist-guided pre-emptive pharmacogenetic testing in antidepressant therapy (PrePGx): study protocol for an open-label, randomized controlled trial. Trials, 22(1), 919. https://doi.org/10.1186/s13063-021-05724-5

Stäuble, Céline K., Lampert, Markus L., Mikoteit, Thorsten, Hatzinger, Martin, Hersberger, Kurt E., & Meyer Zu Schwabedissen, Henriette E. (2021). Severe Adverse Drug Reactions to Quetiapine in Two Patients Carrying; CYP2D6; *4 Variants: A Case Report. International Journal of Molecular Siences, 22(12), 6480. https://doi.org/10.3390/ijms22126480

Stäuble, Céline K, Lampert, Markus L, Mikoteit, Thorsten, Hatzinger, Martin, Hersberger, Kurt E, & Meyer Zu Schwabedissen, Henriette E. (2021). Pharmacogenetic-Guided Antidepressant Selection as an Opportunity for Interprofessional Collaboration: A Case Report. Life (Basel, Switzerland), 11(7), 673. https://doi.org/10.3390/life11070673

Brecht, K., Schäfer, A. M., & Meyer Zu Schwabedissen, H. E. (2020). Uptake transporters of the SLC21, SLC22A, and SLC15A families in anticancer therapy— modulators of cellular entry or pharmacokinetics? Cancers, 12(8), 1–31. https://doi.org/10.3390/cancers12082263

Bonk, Sarah, Hertel, Johannes, Zacharias, Helena U., Terock, Jan, Janowitz, Deborah, Homuth, Georg, Nauck, Matthias, Völzke, Henry, Meyer Zu Schwabedissen, Henriette, Van der Auwera, Sandra, & Grabe, Hans Jörgen. (2020). Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders. Scientific Reports, 10(1), 22394. https://doi.org/10.1038/s41598-020-79388-7

Brecht, Karin, Schäfer, Anima Magdalena, & Meyer zu Schwabedissen, Henriette E. (2020). Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy - Modulators of Cellular Entry or Pharmacokinetics? Cancers, 12(8), 2263–2294. https://doi.org/10.3390/cancers12082263

Ehrsam, Daniel, Sieber, Sandro, Oufir, Mouhssin, Porta, Fabiola, Hamburger, Matthias, Huwyler, Jörg, & Meyer zu Schwabedissen, Henriette E. (2020). Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9. Bioconjugate Chemistry, 31(3), 781–793. https://doi.org/10.1021/acs.bioconjchem.9b00865

Huynh, Christine, Dingemanse, Jasper, Meyer zu Schwabedissen, Henriette E, & Sidharta, Patricia N. (2020). Relevance of the CXCR4/CXCR7-CXCL12 axis and its effect in pathophysiological conditions. Pharmacological Research, 161, 105092. https://doi.org/10.1016/j.phrs.2020.105092

Meyer zu Schwabedissen, Henriette E, Seibert, Isabell, Grube, Markus, Alter, Claudio L, Siegmund, Werner, & Hussner, Janine. (2020). Genetic variants of SLCO1B7 are of relevance for the transport function of OATP1B3-1B7. Pharmacological Research, 161, 105155. https://doi.org/10.1016/j.phrs.2020.105155

Meyer zu Schwabedissen, Henriette, & Schäfer, Anima. (2020). Schweizer Johanniskraut Präparat Hyperforin-armer Extrakt ohne pharmakokinetische Interaktionen. Pharmazeutische Zeitung, 166(27), 1812–1815.

Nicolussi, Simon, Drewe, Jürgen, Butterweck, Veronika, & Meyer zu Schwabedissen, Henriette E. (2020). Clinical relevance of St. John’s wort drug interactions revisited. British Journal of Pharmacology, 177(6), 1212–1226. https://doi.org/10.1111/bph.14936

Schäfer, Anima M, Meyer zu Schwabedissen, Henriette E, Bien-Möller, Sandra, Hubeny, Andrea, Vogelgesang, Silke, Oswald, Stefan, & Grube, Markus. (2020). OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists. Molecular Pharmaceutics, 17(6), 1987–1995. https://doi.org/10.1021/acs.molpharmaceut.0c00159

Stäuble, Céline K, Lampert, Markus L, Mikoteit, Thorsten, Hatzinger, Martin, Hersberger, Kurt E, & Meyer zu Schwabedissen, Henriette E. (2020). Nonresponse to high-dose bupropion for depression in a patient carrying; CYP2B6; *6 and; CYP2C19; *17 variants: a case report. Pharmacogenomics, 21(16), 1145–1150. https://doi.org/10.2217/pgs-2020-0087

Ehrsam, Daniel, Porta, Fabiola, Hussner, Janine, Seibert, Isabell, & Meyer Zu Schwabedissen, Henriette E. (2019). PDMS-PMOXA-Nanoparticles Featuring a Cathepsin B-Triggered Release Mechanism. Materials, 12(17), 2836. https://doi.org/10.3390/ma12172836

Ehrsam, Daniel, Porta, Fabiola, Mori, Matteo, Meyer zu Schwabedissen, Henriette E., Dalla Via, Lisa, Garcia-Argaez, Aìda Nelly, Basile, Livia, Meneghetti, Fiorella, Villa, Stefania, & Gelain, Arianna. (2019). Unravelling the Antiproliferative Activity of 1,2,5-oxadiazole Derivatives. Anticancer Research, 39(7), 3453–3461. https://doi.org/10.21873/anticanres.13491

Ferreira, Celio, Meyer, Ramona, & Meyer Zu Schwabedissen, Henriette E. (2019). The nuclear receptors PXR and LXR are regulators of the scaffold protein PDZK1. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 1862(4), 447–456. https://doi.org/10.1016/j.bbagrm.2019.02.007

Leuppi-Taegtmeyer, Anne, Duthaler, Urs, Hammann, Felix, Schmid, Yasmin, Dickenmann, Michael, Amico, Patricia, Jehle, Andreas W., Kalbermatter, Stefan, Lenherr, Christoph, Meyer Zu Schwabedissen, Henriette E., Haschke, Manuel, Liechti, Matthias E., & Krähenbühl, Stephan. (2019). Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions. Nephrology, Dialysis, Transplantation, 34(4), 692–702. https://doi.org/10.1093/ndt/gfy285

Malagnino, Vanessa, Duthaler, Urs, Seibert, Isabell, Krähenbühl, Stephan, & Meyer Zu Schwabedissen, Henriette E. (2019). OATP1B3-1B7 (LST-3TM12) Is a Drug Transporter That Affects Endoplasmic Reticulum Access and the Metabolism of Ezetimibe. Molecular Pharmacology, 96(2), 128–137. https://doi.org/10.1124/mol.118.114934

Malagnino, Vanessa, Hussner, Janine, Issa, Ali, Midzic, Angela, & Meyer zu Schwabedissen, Henriette E. (2019). OATP1B3-1B7 a novel Organic Anion Transporting Polypeptide is modulated by FXR ligands and transports bile acids. American Journal of Physiology. Gastrointestinal and Liver Physiology, 317(6), G751–G762. https://doi.org/10.1152/ajpgi.00330.2018

Schäfer, Anima M., Potterat, Olivier, Seibert, Isabell, Fertig, Orlando, & Meyer Zu Schwabedissen, Henriette E. (2019). Hyperforin-Induced Activation of the Pregnane X Receptor Is Influenced by the Organic Anion-Transporting Polypeptide 2B1. Molecular Pharmacology, 95(3), 313–323. https://doi.org/10.1124/mol.118.114066

Vizeli, Patrick, Meyer Zu Schwabedissen, Henriette E., & Liechti, Matthias E. (2019). Role of serotonin transporter and receptor gene variations in the acute effects of MDMA in healthy subjects. ACS chemical neuroscience, 10(7), 3120–3131. https://doi.org/10.1021/acschemneuro.8b00590

Witzigmann, Dominik, Uhl, Philipp, Sieber, Sandro, Kaufman, Christina, Einfalt, Tomaz, Schöneweis, Katrin, Grossen, Philip, Buck, Jonas, Ni, Yi, Schenk, Susanne H., Hussner, Janine, Meyer Zu Schwabedissen, Henriette E., Québatte, Gabriela, Mier, Walter, Urban, Stephan, & Huwyler, Jörg. (2019). Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide. eLife, 8, e42276. https://doi.org/10.7554/elife.42276

Meyer zu Schwabedissen, Henriette, & Hersberger, Kurt E. (2019). Pharmakogenetik: Einfluss der Gene auf Medikamente. In Personalisierte Medizin. Grundlagen für die interprofessionelle Aus-, Weiter- und Fortbildung von Gesundheitsfachleuten (Vol. 14, pp. 70–76). Schweizerische Akademie der Medizinischen Wissenschaften. https://doi.org/10.5281/zenodo.3265194

Culverhouse, RC., Saccone, NL., Horton, AC., Ma, Y., Anstey, KJ., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, HL., Goldman, N., Horwood, J., Juhasz, G., Lester, KJ., Mandelli, L., Middeldorp, CM., Olié, E., Villafuerte, S., Air, TM., et al. (2018). Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry, 23(1), 133–142. https://doi.org/10.1038/mp.2017.44

Duthaler, Urs, Suenderhauf, Claudia, Karlsson, Mats O., Hussner, Janine, Meyer Zu Schwabedissen, Henriette, Krähenbühl, Stephan, & Hammann, Felix. (2018). Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers. British Journal of Clinical Pharmacology, 85(3), 626–633. https://doi.org/10.1111/bcp.13840

Ferreira, Celio, Hagen, Paul, Stern, Melanie, Hussner, Janine, Zimmermann, Uwe, Grube, Markus, & Meyer zu Schwabedissen, Henriette E. (2018). The scaffold protein PDZK1 modulates expression and function of the organic anion transporting polypeptide 2B1. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 120, 181–190. https://doi.org/10.1016/j.ejps.2018.05.006

Ferreira, Celio, Prestin, Katharina, Hussner, Janine, Zimmermann, Uwe, & Meyer zu Schwabedissen, Henriette E. (2018). PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ. Molecular and Cellular Endocrinology, 461, 215–225. https://doi.org/10.1016/j.mce.2017.09.017

Malagnino, Vanessa, Hussner, Janine, Seibert, Isabell, Stolzenburg, Antje, Sager, Christoph P., & Meyer zu Schwabedissen, Henriette E. (2018). LST-3TM12 is a member of the OATP1B family and a functional transporter. Biochemical Pharmacology, 148, 75–87. https://doi.org/10.1016/j.bcp.2017.12.012

Meyer zu Schwabedissen, Henriette E., Ferreira, Celio, Schaefer, Anima M., Oufir, Mouhssin, Seibert, Isabell, Hamburger, Matthias, & Tirona, Rommel G. (2018). Thyroid hormones are transport substrates and transcriptional regulators of Organic Anion Transporting Polypeptide 2B1. Molecular Pharmacology, 94(1), 700–712. https://doi.org/10.1124/mol.117.111161

Porta, Fabiola, Ehrsam, Daniel, Lengerke, Claudia, & Meyer Zu Schwabedissen, Henriette E. (2018). Synthesis and characterization of a PDMS-PMOXA based polymersomes sensitive to MMP-9 for application in breast cancer. Molecular Pharmaceutics, 15(11), 4884–4897. https://doi.org/10.1021/acs.molpharmaceut.8b00521

Schäfer, Anima M., Bock, Thomas, & Meyer Zu Schwabedissen, Henriette E. (2018). Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1. Molecular Pharmaceutics, 15(12), 5501–5513. https://doi.org/10.1021/acs.molpharmaceut.8b00631

Terock, Jan, Van der Auwera, Sandra, Janowitz, Deborah, Homuth, Georg, Hannemann, Anke, Schmidt, Carsten Oliver, Meyer Zu Schwabedissen, Henriette, Freyberger, Harald J., & Grabe, Hans Jörgen. (2018). Childhood Trauma and Functional Variants of 5-HTTLPR Are Independently Associated with Alexithymia in 5,283 Subjects from the General Population. Psychotherapy and Psychosomatics, 87(1), 58–61. https://doi.org/10.1159/000484143

Teumer, Alexander, Chaker, Layal, Groeneweg, Stefan, Li, Yong, Di Munno, Celia, Barbieri, Caterina, Schultheiss, Ulla T., Traglia, Michela, Ahluwalia, Tarunveer S., Akiyama, Masato, Appel, Emil Vincent R., Arking, Dan E., Arnold, Alice, Astrup, Arne, Beekman, Marian, Beilby, John P., Bekaert, Sofie, Boerwinkle, Eric, Brown, Suzanne J., et al. (2018). Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nature Communications, 9(1), 4455. https://doi.org/10.1038/s41467-018-06356-1

Vizeli, Patrick, Meyer Zu Schwabedissen, Henriette E., & Liechti, Matthias E. (2018). No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA. European Journal of Clinical Pharmacology, 74(3), 275–283. https://doi.org/10.1007/s00228-017-2392-2

Kim, M., Deacon, P., Tirona, RG., Kim, RB., Pin, CL., Meyer zu Schwabedissen, HE., Wang, R., & Schwarz, UI. (2017). Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas. Histochemistry and Cell Biology, 148(4), 345–357. https://doi.org/10.1007/s00418-017-1580-6

Monzel, Judith V., Budde, Thomas, Meyer zu Schwabedissen, Henriette E., Schwebe, Mattihas, Bien-Möller, Sandra, Lütjohann, Dieter, Kroemer, Heyo K., Jedlitschky, Gabriele, & Grube, Markus. (2017). Doxorubicin enhance oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters. Biochemical Pharmacology, 144, 108–119. https://doi.org/10.1016/j.bcp.2017.08.008

Nolte, IM., Munoz, ML., Tragante, V., Amare, AT., Jansen, R., Vaez, A., von der Heyde, B., Avery, CL., Bis, JC., Dierckx, B., van Dongen, J., Gogarten, SM., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, SJ., Jaju, D., Kerr, KF., Kluttig, A., et al. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications, 8, 15805. https://doi.org/10.1038/ncomms15805

Prestin, Katharina, Hussner, Janine, Ferreira, Celio, Seibert, Isabell, Breitung, Vivien, Zimmermann, Uwe, & Meyer Zu Schwabedissen, Henriette Elisabeth. (2017). Regulation of PDZ domain containing 1 (PDZK1) Expression by Hepatocyte Nuclear Factor 1 alpha (HNF1α) in Human Kidney. American Journal of Physiology - Renal Physiology, 313(4), F973–F983. https://doi.org/10.1152/ajprenal.00650.2016

Prestin, Katharina, Olbert, Maria, Hussner, Janine, Völzke, Henry, & Meyer zu Schwabedissen, Henriette E. (2017). Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2). Pharmacogenetics and Genomics, 27(11), 410–415. https://doi.org/10.1097/fpc.0000000000000310

Vizeli, Patrick, Schmid, Yasmin, Prestin, Katharina, Meyer Zu Schwabedissen, Henriette E., & Liechti, Matthias E. (2017). Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects. European Neuropsychopharmacology, 27(3), 232–238. https://doi.org/10.1016/j.euroneuro.2017.01.008

Gliesche, Daniel G., Hussner, Janine, Witzigmann, Dominik, Porta, Fabiola, Glatter, Timo, Schmidt, Alexander, Huwyler, Jörg, & Meyer Zu Schwabedissen, Henriette E. (2016). Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries. Molecular Pharmaceutics, 13(7), 2290–2300. https://doi.org/10.1021/acs.molpharmaceut.6b00033

Grabe, Hans Jörgen, Wittfeld, Katharina, Van der Auwera, Sandra, Janowitz, Deborah, Hegenscheid, Katrin, Habes, Mohamad, Homuth, Georg, Barnow, Sven, John, Ulrich, Nauck, Matthias, Völzke, Henry, Meyer zu Schwabedissen, Henriette, Freyberger, Harald Jürgen, & Hosten, Norbert. (2016). Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample. Human Brain Mapping, 37(4), 1602–1613. https://doi.org/10.1002/hbm.23123

Hussner, Janine, Sünwoldt, Juliane, Seibert, Isabell, Gliesche, Daniel G., & Meyer zu Schwabedissen, Henriette E. (2016). Pimecrolimus increases the expression of interferon-inducible genes that modulate human coronary artery cells proliferation. European Journal of Pharmacology, 784, 137–146. https://doi.org/10.1016/j.ejphar.2016.05.020

Petersen, Svea, Gliesche, Daniel G., Kurtbay, Güven, Begunk, Robert, Boeck, Maria, Hopf, Verena, Kroemer, Heyo K., Schmitz, Klaus-Peter, Meyer zu Schwabedissen, Henriette E., & Sternberg, Katrin. (2016). Tailored surface design of biodegradable endovascular implants by functionalization of poly (L-lactide) with elastin-like proteins. Journal of Biomedical Engineering and Informatics, 2(1), 52–64. https://doi.org/10.5430/jbei.v2n1p52

Prestin, Katharina, Olbert, Maria, Hussner, Janine, Isenegger, Tamara L., Gliesche, Daniel G., Böttcher, Kerstin, Zimmermann, Uwe, & Meyer Zu Schwabedissen, Henriette E. (2016). Modulation of expression of the nuclear receptor NR0B2 (small heterodimer partner 1) and its impact on proliferation of renal carcinoma cells. OncoTargets and Therapy, 9, 4867–4878. https://doi.org/10.2147/ott.s106926

Schmid, Yasmin, Vizeli, Patrick, Hysek, Cédric M., Prestin, Katharina, Meyer Zu Schwabedissen, Henriette E., & Liechti, Matthias E. (2016). CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals. Pharmacogenetics and Genomics, 26(8), 397–401. https://doi.org/10.1097/fpc.0000000000000231

Schmid, Yasmin, Vizeli, Patrick, Hysek, Cédric M., Prestin, Katharina, Meyer Zu Schwabedissen, Henriette E., & Liechti, Matthias E. (2016). CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals. Pharmacogenetics and Genomics, 26, 397–401. https://doi.org/10.1097/fpc.0000000000000231

Dannlowski, U, Grabe, H J, Wittfeld, K, Klaus, J, Konrad, C, Grotegerd, D, Redlich, R, Suslow, T, Opel, N, Ohrmann, P, Bauer, J, Zwanzger, P, Laeger, I, Hohoff, C, Arolt, V, Heindel, W, Deppe, M, Domschke, K, Hegenscheid, K, et al. (2015). Multimodal imaging of a tescalcin (TESC)-regulating polymorphism (rs7294919) - specific effects on hippocampal gray matter structure. Molecular Psychiatry, 20(3), 398–404. https://doi.org/10.1038/mp.2014.39

Herzog, Susann, Fink, Matthias Alexander, Weitmann, Kerstin, Friedel, Claudius, Hadlich, Stefan, Langner, Sönke, Kindermann, Katharina, Holm, Tobias, Böhm, Andreas, Eskilsson, Eskil, Miletic, Hrvoje, Hildner, Markus, Fritsch, Michael, Vogelgesang, Silke, Havemann, Christoph, Ritter, Christoph Alexander, Meyer zu Schwabedissen, Henriette Elisabeth, Rauch, Bernhard, Hoffmann, Wolfgang, et al. (2015). Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. Neuro-Oncology, 17(2), 223–242. https://doi.org/10.1093/neuonc/nou216

Hussner, Janine, Begung, Robert, Boettcher, Kerstin, Gliesche, Daniel G., Prestin, Katharina, & Meyer zu Schwabedissen, Henriette E. (2015). Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery. Vascular Pharmacology, 72, 25–34. https://doi.org/10.1016/j.vph.2015.06.006

Meyer zu Schwabedissen, H. E., Albers, M., Baumeister, S. E., Rimmbach, C., Nauck, M., Siegmund, W., Voelzke, H., & Kromer, H. K. (2015). Function impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify therapeutic efficacy of statins in a population based cohort. Pharmacogenetics and genomics, 25(1), 8–18. https://doi.org/10.1097/fpc.0000000000000098

Meyer Zu Schwabedissen, H. E. (2015). The role of pharmacogenomics in individualized medicine. Advances in Predictive, Preventive and Personalised Medicine, 7, 93–112. https://doi.org/10.1007/978-3-319-11719-5_7

Haring, R., Friedrich, N., Völzke, H., Vasan, R. S., Felix, S. B., Dörr, M., Meyer Zu Schwabedissen, H. E., Nauck, M., & Wallaschofski, H. (2014). Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality. European Heart Journal, 35(18), 1215–1221. https://doi.org/10.1093/eurheartj/ehs233

Arking, DE, Pulit, SL, Crotti, L, van der Harst, P, Munroe, PB, Koopmann, TT, Sotoodehnia, N, Rossin, EJ, Morley, M, Wang, X, Johnson, AD, Lundby, A, Gudbjartsson, DF, Noseworthy, PA, Eijgelsheim, M, Bradford, Y, Tarasov, KV, Dörr, M, Müller-Nurasyid, M, et al. (2014). Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46(8), 826–836. https://doi.org/10.1038/ng.3014

Grabe, Hans J, Assel, Heinrich, Bahls, Thomas, Dörr, Marcus, Endlich, Karlhans, Endlich, Nicole, Erdmann, Pia, Ewert, Ralf, Felix, Stephan B, Fiene, Beate, Fischer, Tobias, Flessa, Steffen, Friedrich, Nele, Gadebusch-Bondio, Mariacarla, Salazar, Manuela Gesell, Hammer, Elke, Haring, Robin, Havemann, Christoph, Hecker, Michael, et al. (2014). Cohort profile: Greifswald Approach to Individualized Medicine (GANI_MED). Journal of Translational Medicine, 12(1), 144. https://doi.org/10.1186/1479-5876-12-144

Medici, Marco, Porcu, Eleonora, Pistis, Giorgio, Teumer, Alexander, Brown, Suzanne J, Jensen, Richard A, Rawal, Rajesh, Roef, Greet L, Plantinga, Theo S, Vermeulen, Sita H, Lahti, Jari, Simmonds, Matthew J, Husemoen, Lise Lotte N, Freathy, Rachel M, Shields, Beverley M, Pietzner, Diana, Nagy, Rebecca, Broer, Linda, Chaker, Layal, et al. (2014). Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genetics, 10(2), e1004123. https://doi.org/10.1371/journal.pgen.1004123

Meyer Zu Schwabedissen, Henriette E, Begunk, Robert, Hussner, Janine, Juhnke, B Ole, Gliesche, Daniel, Böttcher, Kerstin, Sternberg, Katrin, Schmitz, Klaus-Peter, & Kroemer, Heyo K. (2014). Cell specific expression of uptake transporters - a potential approach for cardiovascular drug delivery devices. Molecular Pharmaceutics, 11(3), 665–672. https://doi.org/10.1021/mp400245g

Meyer Zu Schwabedissen, Henriette E, Boettcher, Kerstin, Steiner, Tobias, Schwarz, Ute I, Keiser, Markus, Kroemer, Heyo K, & Siegmund, Werner. (2014). OATP1B3 is expressed in pancreatic β-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide. Diabetes, 63(2), 775–784. https://doi.org/10.2337/db13-1005

Meyer zu Schwabedissen, Henriette E, Siegmund, Werner, Kroemer, Heyo K, & Rollnik, Jens D. (2014). Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C < T variants: a case report. BMC Research Notes, 7, 688. https://doi.org/10.1186/1756-0500-7-688