Tristan Lee Department of Clinical Research Profiles & Affiliations OverviewResearch Publications Publications by Type Projects & Collaborations Academic Activities Academic Self-Administration Continuing Education Junior Development, Doctorate and Advanced Studies Academic Reputation & Networking Teaching Bachelor/Master Projects & Collaborations OverviewResearch Publications Publications by Type Projects & Collaborations Academic Activities Academic Self-Administration Continuing Education Junior Development, Doctorate and Advanced Studies Academic Reputation & Networking Teaching Bachelor/Master Profiles & Affiliations Projects & Collaborations 3 foundShow per page10 10 20 50 Towards an efficient use of available data in clinical research: Development, validation, and implementation of innovative statistical approaches in causal inference Research Project | 4 Project MembersThis project develops and enhances G-methods to improve causal inference in clinical research by combining longitudinal data with advanced statistical techniques, addressing time-varying treatments, confounders, and spatial correlations. LoDoCA: Tolerability of Ritonavir-Boosted Lopinavir- Vs Dolutegravir-Based Antiretroviral Therapy for Children and Adolescents Living with HIV: an Open-Label Randomised Study in Lesotho, Southern Africa Research Project | 16 Project MembersLoDoCA is a prospective cohort study among children and adolescents with HIV in Lesotho, southern Africa who changed from an antiretroviral therapy regimen containing lopinavir to a regimen containing dolutegravir. The study compares treatment satisfaction and previously reported adverse effects of either drug, including neuropsychiatric (sleep, depression) and gastrointestinal outcomes. Sleep is a key focus, as sleep disturbance has previously been reported as an adverse effect of dolutegravir among adults. Thus, sleep is measured by actigraphy (movement-sensing devices worn by participants around their wrist from around bedtime to morning) in addition to questionnaires. ComBaCaL: Community-based Chronic Care Lesotho Research Project | 13 Project MembersCommunity-based Chronic Care Lesotho is a five-year implementation research project addressing chronic disease care in remote villages in rural Lesotho. In a cohort of over 100 villages we assess through cluster-randomized trials within cohorts (TwiCs) different innovative models where ehealth assisted lay community health workers provide care for hypertension, diabetes and HIV. 1 1 OverviewResearch Publications Publications by Type Projects & Collaborations Academic Activities Academic Self-Administration Continuing Education Junior Development, Doctorate and Advanced Studies Academic Reputation & Networking Teaching Bachelor/Master
Projects & Collaborations 3 foundShow per page10 10 20 50 Towards an efficient use of available data in clinical research: Development, validation, and implementation of innovative statistical approaches in causal inference Research Project | 4 Project MembersThis project develops and enhances G-methods to improve causal inference in clinical research by combining longitudinal data with advanced statistical techniques, addressing time-varying treatments, confounders, and spatial correlations. LoDoCA: Tolerability of Ritonavir-Boosted Lopinavir- Vs Dolutegravir-Based Antiretroviral Therapy for Children and Adolescents Living with HIV: an Open-Label Randomised Study in Lesotho, Southern Africa Research Project | 16 Project MembersLoDoCA is a prospective cohort study among children and adolescents with HIV in Lesotho, southern Africa who changed from an antiretroviral therapy regimen containing lopinavir to a regimen containing dolutegravir. The study compares treatment satisfaction and previously reported adverse effects of either drug, including neuropsychiatric (sleep, depression) and gastrointestinal outcomes. Sleep is a key focus, as sleep disturbance has previously been reported as an adverse effect of dolutegravir among adults. Thus, sleep is measured by actigraphy (movement-sensing devices worn by participants around their wrist from around bedtime to morning) in addition to questionnaires. ComBaCaL: Community-based Chronic Care Lesotho Research Project | 13 Project MembersCommunity-based Chronic Care Lesotho is a five-year implementation research project addressing chronic disease care in remote villages in rural Lesotho. In a cohort of over 100 villages we assess through cluster-randomized trials within cohorts (TwiCs) different innovative models where ehealth assisted lay community health workers provide care for hypertension, diabetes and HIV. 1 1
Towards an efficient use of available data in clinical research: Development, validation, and implementation of innovative statistical approaches in causal inference Research Project | 4 Project MembersThis project develops and enhances G-methods to improve causal inference in clinical research by combining longitudinal data with advanced statistical techniques, addressing time-varying treatments, confounders, and spatial correlations.
LoDoCA: Tolerability of Ritonavir-Boosted Lopinavir- Vs Dolutegravir-Based Antiretroviral Therapy for Children and Adolescents Living with HIV: an Open-Label Randomised Study in Lesotho, Southern Africa Research Project | 16 Project MembersLoDoCA is a prospective cohort study among children and adolescents with HIV in Lesotho, southern Africa who changed from an antiretroviral therapy regimen containing lopinavir to a regimen containing dolutegravir. The study compares treatment satisfaction and previously reported adverse effects of either drug, including neuropsychiatric (sleep, depression) and gastrointestinal outcomes. Sleep is a key focus, as sleep disturbance has previously been reported as an adverse effect of dolutegravir among adults. Thus, sleep is measured by actigraphy (movement-sensing devices worn by participants around their wrist from around bedtime to morning) in addition to questionnaires.
ComBaCaL: Community-based Chronic Care Lesotho Research Project | 13 Project MembersCommunity-based Chronic Care Lesotho is a five-year implementation research project addressing chronic disease care in remote villages in rural Lesotho. In a cohort of over 100 villages we assess through cluster-randomized trials within cohorts (TwiCs) different innovative models where ehealth assisted lay community health workers provide care for hypertension, diabetes and HIV.
