PD Dr. med. Arne Mehrkens

Kamenova M, Li E, Soleman J., Fiebig O, Mehrkens A, & Schaeren S. (2023). Posterior stabilization with polyetheretherketone (PEEK) rods and transforaminal lumbar interbody fusion (TLIF) with titanium rods for single-level lumbar spine degenerative disease in patients above 70 years of age. Archives of Orthopaedic and Trauma Surgery, 143(6), 2831–2843. https://doi.org/10.1007/s00402-022-04448-8

Brian A Karamian, Gregory D Schroeder, Mark J Lambrechts, Jose A Canseco, Cumhur Oner, Emiliano Vialle, Shanmuganathan Rajasekaran, Marcel R Dvorak, Lorin M Benneker, Frank Kandziora, Klaus Schnake, Christopher K Kepler, Alexander R Vaccaro, & AO Spine Subaxial Classification Group Members. (2023). An international validation of the AO spine subaxial injury classification system. European Spine Journal, 32(1), 46–54. https://doi.org/10.1007/s00586-022-07467-6

Karamian, B. A., Schroeder, G. D., Lambrechts, M. J., Canseco, J. A., Oner, C., Vialle, E., Rajasekaran, S., Dvorak, M. R., Benneker, L. M., Kandziora, F., Schnake, K., Kepler, C. K., Vaccaro, A. R., Costa, B. L., Estefan, M., Dawoud, A., Kaen, A., Yuh, S.-J., Fuego, S., et al. (2023). An international validation of the AO spine subaxial injury classification system. European Spine Journal, 32(1), 46–54. https://doi.org/10.1007/s00586-022-07467-6

Kasamkattil, Jesil, Gryadunova, Anna, Schmid, Raphael, Gay-Dujak, Max Hans Peter, Dasen, Boris, Hilpert, Morgane, Pelttari, Karoliina, Martin, Ivan, Schären, Stefan, Barbero, Andrea, Krupkova, Olga, & Mehrkens, Arne. (2023). Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc. Frontiers in Bioengineering and Biotechnology, 11. https://doi.org/10.3389/fbioe.2023.1119009

Matta A, Karim MZ, Gerami H, Benigno BZ, Cheng I, Mehrkens A, & Erwin WM. (2022). A Single Injection of NTG-101 Reduces the Expression of Pain-Related Neurotrophins in a Canine Model of Degenerative Disc Disease. International Journal of Molecular Sciences, 23(10). https://doi.org/10.3390/ijms23105717

Gay MH, Born G, Mehrkens A, Wittig H, & Müller-Gerbl M. (2022). Computed tomography osteoabsorptiometry for imaging of degenerative disc disease. North American Spine Society Journal, 9, 100102. https://doi.org/10.1016/j.xnsj.2022.100102

Kasamkattil J, Gryadunova A, Martin I, Barbero A, Schären S, Krupkova O, & Mehrkens A. (2022). Spheroid-Based Tissue Engineering Strategies for Regeneration of the Intervertebral Disc. International Journal of Molecular Sciences, 23(5). https://doi.org/10.3390/ijms23052530

Mainardi, Andrea, Mainardi, Andrea, Cambria, Elena, Occhetta, Paola, Martin, Ivan, Barbero, Andrea, Schären, Stefan, Mehrkens, Arne, & Krupkova, Olga. (2022). Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective. Frontiers in Bioengineering and Biotechnology, 9, 826867. https://doi.org/10.3389/fbioe.2021.826867

Gryadunova A., Kasamkattil J., Gay M.H.P., Dasen B, Pelttari K, Mironov V., Martin I., Scharen S., Barbero A, Krupkova O., & Mehrkens A. (2021). Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Acta Biomaterialia, 134, 240–251. https://doi.org/10.1016/j.actbio.2021.07.064

Stüdle C, Occhetta P, Geier F, Mehrkens A, Barbero A., & Martin I. (2019). Challenges Toward the Identification of Predictive Markers for Human Mesenchymal Stromal Cells Chondrogenic Potential. Stem Cells Translational Medicine, 8(2), 194–204. https://doi.org/10.1002/sctm.18-0147

Gay M.H.P., Mehrkens A, Rittmann M., Haug M, Barbero A., Martin I., & Schaeren S. (2019). Nose to back: Compatibility of nasal chondrocytes with environmental conditions mimicking a degenerated intervertebral disc. European Cells and Materials, 37, 214–323. https://doi.org/10.22203/ecm.v037a13

Rossi E., Mracsko E., Papadimitropoulos A., Allafi N., Reinhardt D., Mehrkens A., Martin I., Knuesel I., & Scherberich A. (2018). An In Vitro Bone Model to Investigate the Role of Triggering Receptor Expressed on Myeloid Cells-2 in Bone Homeostasis. Tissue Engineering - Part C: Methods, 24(7), 391–398. https://doi.org/10.1089/ten.tec.2018.0061

Stüdle C, Vallmajó-Martín Q, Haumer A, Guerrero J, Centola M, Mehrkens A, Schaefer DJ, Ehrbar M, Barbero A, & Martin I. (2018). Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues. Biomaterials, 171, 219–229. https://doi.org/10.1016/j.biomaterials.2018.04.025

Occhetta P., Pigeot S., Rasponi M., Dasen B., Mehrkens A., Ullrich T., Kramer I., Guth-Gundel S., Barbero A., & Martin I. (2018). Developmentally inspired programming of adult human mesenchymal stromal cells toward stable chondrogenesis. Proceedings of the National Academy of Sciences of the United States of America, 115(18), 4625–4630. https://doi.org/10.1073/pnas.1720658115

Veresciagina K, Mehrkens A, Schären S, & Jeanneret B. (2018). Minimum ten-year follow-up of spinal stenosis with degenerative spondylolisthesis treated with decompression and dynamic stabilization. Journal of spine surgery (Hong Kong), 4(1), 93–101. https://doi.org/10.21037/jss.2018.03.20

Hoch AI, Duhr R, Di Maggio N, Mehrkens A, Jakob M, & Wendt D. (2017). Expansion of Bone Marrow Mesenchymal Stromal Cells in Perfused 3D Ceramic Scaffolds Enhances In Vivo Bone Formation. Biotechnology journal, 12(12). https://doi.org/10.1002/biot.201700071

Mehrkens A, Matta A, Karim MZ, Kim S, Fehlings MG, Schaeren S, & Mark Erwin W. (2017). Notochordal cell-derived conditioned medium protects human nucleus pulposus cells from stress-induced apoptosis. The spine journal : official journal of the North American Spine Society, 17(4), 579–588. https://doi.org/10.1016/j.spinee.2017.01.003

Mueller, S., Acevedo, L., Karim, M., Matta, A., Mehrkens, A., Schaeren, S., Jakob, M., Martin, I., Barbero, A., & Erwin, M. (2016). NOTOCHORDAL CELL CONDITIONED MEDIUM ENHANCES THE CARTILAGE MATRIX PRODUCTION AND REDUCES CATABOLISM BY HUMAN ARTICULAR CHONDROCYTES. 24, S169–S169. ELSEVIER SCI LTD.

Leu, Severina, Kamenova, Maria, Mehrkens, Arne, Mariani, Luigi, Schären, Stefan, & Soleman, Jehuda. (2016). Preoperative and Postoperative Factors and Laboratory Values Predicting Outcome in Patients Undergoing Lumbar Fusion Surgery. World Neurosurgery, 92, 323–338. https://doi.org/10.1016/j.wneu.2016.05.011

Müller, Sebastian, Acevedo, Lina, Wang, Xiaomei, Karim, M. Zia, Matta, Ajay, Mehrkens, Arne, Schaeren, Stefan, Feliciano, Sandra, Jakob, Marcel, Martin, Ivan, Barbero, Andrea, & Erwin, W. Mark. (2016). Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype. Arthritis Research and Therapy, 18(1), 125. https://doi.org/10.1186/s13075-016-1026-x

Erwin WM, DeSouza L, Funabashi M, Kawchuk G, Karim MZ, Kim S, Mӓdler S, Matta A, Wang X, & Mehrkens KA. (2015). The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc. Arthritis research & therapy, 17(1), 240. https://doi.org/10.1186/s13075-015-0733-z

Müller MA, Mehrkens A, Zürcher R, Vavken P, & Valderrabano V. (2014). Effectiveness of the addition of Lidocaine to a hemostatic, bioresorbable putty in the treatment of iliac crest donor site pain. BMC musculoskeletal disorders, 15, 415. https://doi.org/10.1186/1471-2474-15-415

Lewis SJ, Keshen SG, Lewis ND, Dear TE, Mehrkens A, & Niazi AU. (2014). Tension Pneumothorax as a Complication of Inadvertent Pleural Tears During Posterior Spinal Surgery. Spine deformity, 2(4), 316–321. https://doi.org/10.1016/j.jspd.2014.04.008

Mehrkens, A., Di Maggio, N., Gueven, S., Schaefer, D., Scherberich, A., Banfi, A., & Martin, I. (2014). Non-adherent mesenchymal progenitors from adipose tissue stromal vascular fraction. Tissue Engineering, 20(5-6), 1081–1088. https://doi.org/10.1089/ten.tea.2013.0273

Mehrkens A., & Jeanneret B. (2014). Neurogenic claudication Claudicatio spinalis. Phlebologie, 43(6), 303–307. https://doi.org/10.12687/phleb2223-6-2014

Mehrkens,A, & Rutz,E. (2014). Complaints of the musculoskeletal system of dragon boaters compared to those of kayakers Beschwerden des bewegungsapparates bei drachenbootsportlern im vergleich zu anderen wassersportarten. Deutsche Zeitschrift Fur Sportmedizin, 65(3), 72–76. https://doi.org/10.5960/dzsm.2014.118

Mehrkens A, Karim MZ, Kim S, Hilario R, Fehlings MG, & Erwin WM. (2013). Canine notochordal cell-secreted factors protect murine and human nucleus pulposus cells from apoptosis by inhibition of activated caspase-9 and caspase-3/7. Evidence-based spine-care journal, 4(2), 154–156. https://doi.org/10.1055/s-0033-1357363

Müller MA, Frank A, Briel M, Valderrabano V, Vavken P, Entezari V, & Mehrkens A. (2013). Substitutes of structural and non-structural autologous bone grafts in hindfoot arthrodeses and osteotomies: a systematic review. BMC musculoskeletal disorders, 14, 59. https://doi.org/10.1186/1471-2474-14-59

Mehrkens A, Müller AM, Valderrabano V, Schären S, & Vavken P. (2012). Tissue engineering approaches to degenerative disc disease--a meta-analysis of controlled animal trials. Osteoarthritis and cartilage, 20(11), 1316–1325. https://doi.org/10.1016/j.joca.2012.06.001

Di Maggio, Nunzia, Mehrkens, Arne, Papadimitropoulos, Adam, Schaeren, Stefan, Heberer, Michael, Banfi, Andrea, & Martin, Ivan. (2012). Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells, 30(7), 1455–1464. https://doi.org/10.1002/stem.1106

Müller,C.W., Noll,C, Krettek,C, Mehrkens,A, & Mameghani,A. (2012). Was gibt es neues in der Wirbelsäulenchirurgie? In Ecomed Medizin, Landsberg/Lech: Vol. 5.2 (pp. 305–318).

Güven, Sinan, Mehrkens, Arne, Saxer, Franziska, Schaefer, Dirk J., Martinetti, Roberta, Martin, Ivan, & Scherberich, Arnaud. (2011). Engineering of large osteogenic grafts with rapid engraftment capacity using mesenchymal and endothelial progenitors from human adipose tissue. Biomaterials, 32(25), 5801–5809. https://doi.org/10.1016/j.biomaterials.2011.04.064

Hasler, Carol-Claudius, Mehrkens, Arne, & Hefti, Fritz. (2010). Efficacy and safety of VEPTR instrumentation for progressive spine deformities in young children without rib fusions. European Spine Journal, 19(3), 400–408. https://doi.org/10.1007/s00586-009-1253-9

Mehrkens,A. (2010). Leichtathletik. In Deutscher Aerzteverlag Koeln: Vol. 3.13 (pp. 287–289).

Mehrkens,A, Müller,AM, & Valderrabano,V. (2010). Thromboseprophylaxe in der Orthopädie und Traumatologie –eine Übersicht über die gebräuchlichsten Produkte. Swiss Knife, 3(5), 14–18.

Müller,A M, Mehrkens,A, Leumann,A, & Valderrabano,V. (2010). Orthobiologics in der Fuß- und Sprunggelenk-Sportorthopädie. In Deutscher Aerzteverlag Koeln: Vol. 2.15 (pp. 232–246).

Steuber,K U, & Mehrkens,A. (2010). Motorsportarten. In Deutscher Aerzteverlag Koeln: Vol. 3.14 (pp. 290–291).

Papadimitropoulos A., Mehrkens A., Theilgaard N., Scherberich A., Scherberich A., & Martin I. (2009). An in vitro model of bone organ starting from progenitor cell populations. 18, 56.

Rosso,C, Mehrkens,A, & Valderrabano,V. (2009). Verletzungsrisiko bei Karate, Taekwondo & Co. Orthopädie Rheuma, 11(4), 41–44.

Mehrkens,KA, Kayhan,N, Ell,N, Schuppe,A, Hagl,S, & Vahl,CF. (2003). Effects of acute ethanol exposure on isolated human myocardium. Zeitschrift Fur Herz-, Thorax- Und Gefasschirurgie, 17(6), 247–256. https://doi.org/10.1007/s00398-003-0412-2

Blattler, W, & Marshall, M. (1999). Intermittent claudication: Ischaemic, venous, neurogenic or ... PHLEBOLOGIE, 28, 153–155.

Vahl CF, Kloss T, Yang Y, Castell M, Mehrkens A, deSimone R, Schäffer L, & Hagl S. (1999). Surgical treatment of oligosymptomatic mitral valve incompetence? European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 16(5), 524–532. https://doi.org/10.1016/s1010-7940(99)00231-6