Ultimately, I aim to improve diagnosis for certain diseases, to better phenotype complex pathophysiological processes, as well as to personalize therapy. My breath analysis lab houses a state-of-the art mass spectrometric analytical platform for real-time analysis of exhaled breath and an efficient numerically-optimized Secondary Electrospray Ionization source coupled with a high resolution mass spectrometer. In addition, the lab is equipped with an Ultra High Pressure Liquid Chromatography system, which, coupled with the mass spectrometer, is dedicated for metabolite identification. Bio-informatic tools developed in my lab unravel biochemical information encoded in the mass spectral fingerprints of our patients.