Prof. Dr. med. Mirjam Christ-Crain

Wälchli-Popovic, Milica, Monnerat, Sophie, Taylor, Angela E., Gilligan, Lorna C., Schiffer, Lina, Arlt, Wiebke, Vogt, Deborah R., De Geyter, Christian, Hutter, Nina, Donath, Marc Y., Sartorius, Gideon, & Christ-Crain, Mirjam. (2024). Effects of interleukin-1 receptor antagonism in women with polycystic ovary syndrome—the FertIL trial [Journal-article]. Frontiers in Endocrinology, 15. https://doi.org/10.3389/fendo.2024.1435698

Fleseriu, M., Christ-Crain, M., Langlois, F., Gadelha, M., & Melmed, S. (2024). Hypopituitarism. The Lancet, 403(10444), 2632–2648. https://doi.org/10.1016/s0140-6736(24)00342-8

Lüthi, Hualin, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Laager, Mirjam, Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., et al. (2024). Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial [Journal-article]. eClinicalMedicine, 68, 102429. https://doi.org/10.1016/j.eclinm.2024.102429

Lüthi, Hualin, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Laager, Mirjam, Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., et al. (2024). Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial [Journal-article]. eClinicalMedicine, 68, 102429. https://doi.org/10.1016/j.eclinm.2024.102429

Lüthi, Hualin, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Laager, Mirjam, Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., et al. (2024). Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial [Journal-article]. eClinicalMedicine, 68, 102429. https://doi.org/10.1016/j.eclinm.2024.102429

Atila, Cihan, Beck, Julia, Refardt, Julie, Erlic, Zoran, Drummond, Juliana B., Sailer, Clara O., Liechti, Matthias E., Rocha, Beatriz Santana Soares, Beuschlein, Felix, Winzeler, Bettina, & Christ-Crain, Mirjam. (2024). Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls. European Journal of Endocrinology, 190, 354–362. https://doi.org/10.1093/ejendo/lvae040

Atila, Cihan, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Correction to: Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency (Nature Reviews Endocrinology, (2024), 10.1038/s41574-024-00985-x). Nature Reviews Endocrinology. https://doi.org/10.1038/s41574-024-00998-6

Atila, Cihan, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency. Nature Reviews Endocrinology. https://doi.org/10.1038/s41574-024-00985-x

Efthymiadis, Agathoklis, Pofi, Riccardo, Rostom, Hussam, James, Tim, Shine, Brian, Guha, Nish, Cudlip, Simon, Christ-Crain, Mirjam, & Pal, Aparna. (2024). Copeptin and the syndrome of inappropriate antidiuresis (SIAD) after pituitary transsphenoidal surgery. Endocrinology, Diabetes and Metabolism, 7. https://doi.org/10.1002/edm2.467

Huynh, Tony, Signal, Dana, & Christ-Crain, Mirjam. (2024). Paediatric perspectives in the diagnosis of polyuria-polydipsia syndrome. Clinical Endocrinology, null. https://doi.org/10.1111/cen.15011

Kriemler, Lilian, Rudin, Salome, Gawinecka, Joanna, Gross, Felix, Arnold, Markus, Schweizer, Juliane, Westphal, Laura, Inauen, Corinne, Pokorny, Thomas, Dittrich, Tolga, Toebak, Anna, Arnold, Marcel, Christ-Crain, Mirjam, von Eckardstein, Arnold, Rentsch, Katharina, Katan, Mira, & De Marchis, Gian Marco. (2024). Discordance between LDL-C and apolipoprotein B is associated with large-artery-atherosclerosis ischemic stroke in patients ⩽70 years of age. European Stroke Journal, 9, 494–500. https://doi.org/10.1177/23969873231221619

Lüthi, Hualin, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Laager, Mirjam, Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., et al. (2024). Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial. eClinicalMedicine, 68. https://doi.org/10.1016/j.eclinm.2024.102429

Radvanyi, Z., Yoo, E. J., Kandasamy, P., Salas-Bastos, A., Monnerat, S., Refardt, J., Christ-Crain, M., Hayashi, H., Kondo, Y., Jantsch, J., Rubio-Aliaga, I., Sommer, L., Wagner, C. A., Hediger, M. A., Kwon, H. M., Loffing, J., & Pathare, G. (2024). Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation [Journal-article]. Journal of Biological Chemistry, 300, 105480. https://doi.org/10.1016/j.jbc.2023.105480

Refardt, Julie, Vogt, Deborah R., & Christ-Crain, Mirjam. (2024). Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency. New England Journal of Medicine, 390, 288–290. https://doi.org/10.1056/nejmc2314326

Rudin, Salome, Kriemler, Lilian, Dittrich, Tolga D., Zietz, Annaelle, Schweizer, Juliane, Arnold, Markus, Peters, Nils, Barinka, Filip, Jung, Simon, Arnold, Marcel, Fischer, Urs, Rentsch, Katharina, Christ-Crain, Mirjam, Katan, Mira, & De Marchis, Gian Marco. (2024). Lipoprotein(a) as a blood marker for large artery atherosclerosis stroke etiology: validation in a prospective cohort from a swiss stroke center. Swiss Medical Weekly, 154. https://doi.org/10.57187/s.3633

Refardt, J., Atila, C., Chifu, I., Ferrante, E., Erlic, Z., Drummond, J. B., Indirli, R., Drexhage, R. C., Sailer, C. O., Widmer, A., Felder, S., Powlson, A. S., Hutter, N., Vogt, D. R., Gurnell, M., Soares, B. S., Hofland, J., Beuschlein, F., Fassnacht, M., et al. (2023). Arginine or Hypertonic Saline–Stimulated Copeptin to Diagnose AVP Deficiency [Journal-article]. New England Journal of Medicine, 389(20), 1877–1887. https://doi.org/10.1056/nejmoa2306263

Monnerat S, Christ-Crain M, & Refardt J. (2023). One Liter a Day, Keeps the Doctor Away. (Patent No. 11). 108(11), Article 11. https://doi.org/10.1210/clinem/dgad217

Smit, J. M., Van Der Zee, P. A., Stoof, S. C. M., Van Genderen, M. E., Snijders, D., Boersma, W. G., Confalonieri, P., Salton, F., Confalonieri, M., Shih, M.-C., Meduri, G. U., Dequin, P.-F., Le Gouge, A., Lloyd, M., Karunajeewa, H., Bartminski, G., Fernández-Serrano, S., Suárez-Cuartín, G., van Klaveren, D., et al. (2023). Predicting individualized treatment effects of corticosteroids in community-acquired-pneumonia: a data-driven analysis of randomized controlled trials [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.10.03.23296132

Monnerat S, Refardt J, Potasso L, Meier C, & Christ-Crain M. (2023). An Increase in Plasma Sodium Levels Is Associated With an Increase in Osteoblast Function in Chronic SIAD. The Journal of Clinical Endocrinology and Metabolism, 108(10), e1027–e1033. https://doi.org/10.1210/clinem/dgad238

Warren AM, Grossmann M, Christ-Crain M, & Russell N. (2023). Syndrome of Inappropriate Antidiuresis: From Pathophysiology to Management. Endocrine Reviews, 44(5), 819–861. https://doi.org/10.1210/endrev/bnad010

Sterns RH, Rondon-Berrios H, Adrogué HJ, Berl T, Burst V, Cohen DM, Christ-Crain M, Cuesta M, Decaux G, Emmett M, Garrahy A, Gankam-Kengne F, Hix JK, Hoorn EJ, Kamel KS, Madias NE, Peri A, Refardt J, Rosner MH, et al. (2023). Treatment Guidelines for Hyponatremia: Stay the Course. Clinical Journal of the American Society of Nephrology : CJASN. https://doi.org/10.2215/cjn.0000000000000244

Radvanyi, Z., Yoo, E. J., Kandasamy, P., Salas-Bastos, A., Monnerat, S., Refardt, J., Christ-Crain, M., Hayashi, H., Kondo, Y., Jantsch, J., Rubio-Aliaga, I., Sommer, L., Wagner, C. A., Hediger, M. A., Kwon, H. M., Loffing, J., & Pathare, G. (2023). Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.06.23.546282

Pelouto A, Refardt JC, Christ-Crain M, Zandbergen AAM, & Hoorn EJ. (2023). Overcorrection and undercorrection with fixed dosing of bolus hypertonic saline for symptomatic hyponatremia. European Journal of Endocrinology, 188(3), 322–330. https://doi.org/10.1093/ejendo/lvad028

Sailer CO, Gaisl O, Beglinger S, Frech-Dörfler M, Sommer V, Lüthy MH, & Christ-Crain M. (2023). Copeptin improves prediction of treatment response in children with monosymptomatic nocturnal enuresis. European Journal of Endocrinology, 188(3). https://doi.org/10.1093/ejendo/lvad022

Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial [Journal-article]. eClinicalMedicine, 57, 101865. https://doi.org/10.1016/j.eclinm.2023.101865

Workeneh BT, Meena P, Christ-Crain M, & Rondon-Berrios H. (2023). Hyponatremia Demystified: Integrating Physiology to Shape Clinical Practice. Advances in Kidney Disease and Health, 30(2), 85–101. https://doi.org/10.1053/j.akdh.2022.11.004

Monnerat S, Atila C, Refardt J, & Christ-Crain M. (2023). Prevalence of Admission Hyponatremia in Patients With Diabetes Treated With and Without an SGLT2 inhibitor. Journal of the Endocrine Society, 7(4), bvad011. https://doi.org/10.1210/jendso/bvad011

Refardt J, Imber C, Nobbenhuis R, Sailer CO, Haslbauer A, Monnerat S, Bathelt C, Vogt DR, Berres M, Winzeler B, Bridenbaugh SA, & Christ-Crain M. (2023). Treatment Effect of the SGLT2 Inhibitor Empagliflozin on Chronic Syndrome of Inappropriate Antidiuresis: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial. Journal of the American Society of Nephrology : JASN, 34(2), 322–332. https://doi.org/10.1681/asn.2022050623

Arima H, Cheetham T, Christ-Crain M, Cooper DL, Drummond JB, Gurnell M, Levy M, McCormack A, Newell-Price JD, Verbalis JG, & Wass J. (2023). Changing the Name of Diabetes Insipidus: A Position Statement of the Working Group to Consider Renaming Diabetes Insipidus. Hormone Research in Paediatrics, 96(4), 423–425. https://doi.org/10.1159/000527139

Atila, Cihan, Holze, Friederike, Murugesu, Rakithan, Rommers, Nikki, Hutter, Nina, Varghese, Nimmy, Sailer, Clara O, Eckert, Anne, Heinrichs, Markus, Liechti, Matthias E, & Christ-Crain, Mirjam. (2023). Oxytocin in response to MDMA provocation test in patients with arginine vasopressin deficiency (central diabetes insipidus): a single-centre, case-control study with nested, randomised, double-blind, placebo-controlled crossover trial. The Lancet Diabetes and Endocrinology, 11, 454–464. https://doi.org/10.1016/s2213-8587(23)00120-1

Baur, Fabienne, Atila, Cihan, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Bathelt, Cemile, Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Gender differences in weight gain during attempted and successful smoking cessation on dulaglutide treatment: A predefined secondary analysis of a randomised trial. BMJ Nutrition, Prevention and Health, 6, 301–309. https://doi.org/10.1136/bmjnph-2023-000781

Blum, Claudine A., Roethlisberger, Eva A., Cesana-Nigro, Nicole, Winzeler, Bettina, Rodondi, Nicolas, Blum, Manuel R., Briel, Matthias, Mueller, Beat, Christ-Crain, Mirjam, & Schuetz, Philipp. (2023). Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial. BMC Pulmonary Medicine, 23. https://doi.org/10.1186/s12890-023-02794-w

Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Coynel, David, Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Zanchi, Davide, Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Glucagon-like peptide-1 analogues: a new way to quit smoking? (SKIP)—a structured summary of a study protocol for a randomized controlled study. Trials, 24. https://doi.org/10.1186/s13063-023-07164-9

Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Vogt, Deborah R., Hemkens, Lars G., Speich, Benjamin, Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial. eClinicalMedicine, 57. https://doi.org/10.1016/j.eclinm.2023.101865

Monnerat, Sophie, Atila, Cihan, Baur, Fabienne, de Jesus, Joyce Santos, Refardt, Julie, Dickenmann, Michael, & Christ-Crain, Mirjam. (2023). Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study—the TREASURE study. European Journal of Endocrinology, 189, 252–261. https://doi.org/10.1093/ejendo/lvad108

Potasso, Laura, Monnerat, Sophie, Refardt, Julie, Lindner, Gregor, Burst, Volker, Winzeler, Bettina, & Christ-Crain, Mirjam. (2023). Chloride and Potassium Assessment Is a Helpful Tool for Differential Diagnosis of Thiazide-Associated Hyponatremia. Journal of Clinical Endocrinology and Metabolism, 108, 2248–2254. https://doi.org/10.1210/clinem/dgad133

Probst, L., Monnerat, S., Vogt, D. R., Lengsfeld, S., Burkard, T., Meienberg, A., Bathelt, C., Christ-Crain, M., & Winzeler, B. (2023). Effects of dulaglutide on alcohol consumption during smoking cessation. JCI Insight, 8. https://doi.org/10.1172/jci.insight.170419

Refardt, Julie, Atila, Cihan, & Christ-Crain, Mirjam. (2023). New insights on diagnosis and treatment of AVP deficiency. Reviews in Endocrine and Metabolic Disorders, null. https://doi.org/10.1007/s11154-023-09862-w

Roth, Sofia, Flint, Emilio, Ghataore, Lea, Patel, Vishal C., Singanayagam, Arjuna, Vincent, Royce P., Triantafyllou, Evangelos, Ma, Yun, Bernal, William, Auzinger, Georg, Heneghan, Michael, Antoniades, Charalambos, Christ-Crain, Mirjam, McPhail, Mark J.W., Taylor, David R., Wendon, Julia, & Bernsmeier, Christine. (2023). Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Gastro Hep Advances, 2, 72–82. https://doi.org/10.1016/j.gastha.2022.08.006

Arima H, Cheetham T, Christ-Crain M, Cooper D, Drummond J, Gurnell M, Levy M, McCormack A, Newell-Price J, Verbalis JG, Wass J, & Working Group for Renaming Diabetes Insipidus. (2022). Changing the Name of Diabetes Insipidus: A Position Statement of the Working Group for Renaming Diabetes Insipidus. The Journal of Clinical Endocrinology and Metabolism, 108(1), 1–3. https://doi.org/10.1210/clinem/dgac547

Arima H, Bichet DG, Cheetham T, Christ-Crain M, Drummond J, Gurnell M, Levy M, McCormack A, Newell-Price J, Verbalis JG, Wass J, & Cooper D. (2022). Changing the name of diabetes insipidus. (Patent No. 6). 25(6), Article 6. https://doi.org/10.1007/s11102-022-01276-2

Nahum U, Refardt J, Chifu I, Fenske WK, Fassnacht M, Szinnai G, Christ-Crain M, & Pfister M. (2022). Machine learning-based algorithm as an innovative approach for the differentiation between diabetes insipidus and primary polydipsia in clinical practice. European Journal of Endocrinology, 187(6), 777–786. https://doi.org/10.1530/eje-22-0368

Working Group for Renaming Diabetes Insipidus, Arima H, Cheetham T, Christ-Crain M, Cooper D, Gurnell M, Drummond JB, Levy M, McCormack AI, Verbalis J, Newell-Price J, & Wass JAH. (2022). Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus. Endocrine Journal, 69(11), 1281–1284. https://doi.org/10.1507/endocrj.ej20220831

Arima H, Cheetham T, Christ-Crain M, Cooper DL, Drummond JB, Gurnell M, Levy M, McCormack A, Newell-Price JD, Verbalis JG, & Wass J. (2022). Changing the name of diabetes insipidus: a position statement of the working group to consider renaming diabetes insipidus. 66, 868–870. https://doi.org/10.20945/2359-3997000000528

Working Group for Renaming Diabetes Insipidus, Arima H, Cheetham T, Christ-Crain M, Cooper D, Gurnell M, Drummond JB, Levy M, McCormack AI, Verbalis J, Newell-Price J, & Wass JAH. (2022). Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus. Endocrine Connections, 11(11). https://doi.org/10.1530/ec-22-0378

Working Group for Renaming Diabetes Insipidus, Arima H, Cheetham T, Christ-Crain M, Cooper D, Gurnell M, Drummond JB, Levy M, McCormack AI, Verbalis J, Newell-Price J, & Wass JAH. (2022). Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus. European Journal of Endocrinology, 187(5), P1–P3. https://doi.org/10.1530/eje-22-0751

Sailer CO, Kuehne JM, da Conceição I, Refardt J, Christ-Crain M, & Winzeler B. (2022). Hypothalamic-pituitary-adrenal axis activity in patients with primary polydipsia compared to healthy controls. Clinical Endocrinology. https://doi.org/10.1111/cen.14835

Atila C, Loughrey PB, Garrahy A, Winzeler B, Refardt J, Gildroy P, Hamza M., Pal A, Verbalis JG, Thompson CJ, Hemkens L.G., Hunter SJ, Sherlock M, Levy MJ, Karavitaki N., Newell-Price J, Wass JAH, & Christ-Crain M. (2022). Central diabetes insipidus from a patient’s perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey. The Lancet Diabetes and Endocrinology, 10(10), 700–709. https://doi.org/10.1016/s2213-8587(22)00219-4

Atila C, Monnerat S, Bingisser R, Siegemund M, Lampart M, Rueegg M, Zellweger N, Osswald S, Rentsch K, Christ-Crain M, & Twerenbold R. (2022). Inverse relationship between IL-6 and sodium levels in patients with COVID-19 and other respiratory tract infections: data from the COVIVA study. Endocrine Connections, 11(10). https://doi.org/10.1530/ec-22-0171

Arima H, Cheetham T, Christ-Crain M, Cooper D, Drummond J, Gurnell M, Levy M, McCormack A, Newell-Price J, Verbalis JG, & Wass J. (2022, August 28). Changing the name of diabetes insipidus: a position statement of the working group to consider renaming diabetes insipidus. https://doi.org/10.1111/cen.14819

Atila C, Monnerat S, Urwyler SA, Refardt J, Winzeler B, & Christ-Crain M. (2022). The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults : Data from: Glucacop, Macicop, and CARGO study. Pituitary, 25(4), 636–644. https://doi.org/10.1007/s11102-022-01240-0

Bicvic A, Scherrer N, Schweizer J, Fluri F, Christ-Crain M, De Marchis GM, Luft AR, & Katan M. (2022). A novel biomarker panel index improves risk stratification after ischemic stroke. European Stroke Journal, 7(2), 158–165. https://doi.org/10.1177/23969873221090798

Christ-Crain M, Refardt J, & Winzeler B. (2022). Approach to the Patient: “Utility of the Copeptin Assay”. The Journal of Clinical Endocrinology and Metabolism, 107(6), 1727–1738. https://doi.org/10.1210/clinem/dgac070

Vukajlovic T, Sailer CO, Asmar A, Jensen BL, Vogt DR, Christ-Crain M, & Winzeler B. (2022). Effect of a 3-Week Treatment with GLP-1 Receptor Agonists on Vasoactive Hormones in Euvolemic Participants. The Journal of Clinical Endocrinology and Metabolism, 107(6), e2581–e2589. https://doi.org/10.1210/clinem/dgac063

Atila C, Gaisl O, Vogt DR, Werlen L, Szinnai G, & Christ-Crain M. (2022). Glucagon-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a double-blind, randomized, placebo-controlled study. European Journal of Endocrinology, 187(1), 65–74. https://doi.org/10.1530/eje-22-0033

Atila, C., Monnerat, S., Urwyler, S. A., Refardt, J., Winzeler, B., & Christ-Crain, M. (2022, May 12). The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-1636018/v1

Borisov AN, Blum CA, Christ-Crain M, & Ebrahimi F. (2022). No obesity paradox in patients with community-acquired pneumonia - secondary analysis of a randomized controlled trial. Nutrition & Diabetes, 12(1), 12. https://doi.org/10.1038/s41387-022-00190-7

Sailer, C. O., Kühne, J. M., Conceição, I. d., Refardt, J., Christ-Crain, M., & Winzeler, B. (2022, March 3). Hypothalamic-pituitary-adrenal axis activity in patients with primary polydipsia compared to healthy volunteers [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-1370576/v1

Tritos NA, Fazeli PK, McCormack A, Mallea-Gil SM, Pineyro MM, Christ-Crain M, Frara S, Labadzhyan A, Ioachimescu AG, Shimon I, Takahashi Y, Gurnell M, Fleseriu M, & “Pituitary Society Delphi Collaborative Group”. (2022). Pituitary Society Delphi Survey: An international perspective on endocrine management of patients undergoing transsphenoidal surgery for pituitary adenomas. Pituitary, 25(1), 64–73. https://doi.org/10.1007/s11102-021-01170-3

Potasso L, Refardt J, De Marchis GM, Wiencierz A, Wright PR, Wagner B, Dittrich T, Polymeris AA, Gensicke H, Bonati LH, & Christ-Crain M. (2022). Impact of Sodium Levels on Functional Outcomes in Patients With Stroke - A Swiss Stroke Registry Analysis. The Journal of Clinical Endocrinology and Metabolism, 107(2), e672–e680. https://doi.org/10.1210/clinem/dgab650

Liberale, Luca, Ministrini, Stefano, Arnold, Markus, Puspitasari, Yustina M., Pokorny, Thomas, Beer, Georgia, Scherrer, Natalie, Schweizer, Juliane, Christ-Crain, Mirjam, Montecucco, Fabrizio, Camici, Giovanni G., & Katan Kahles, Mira. (2022). Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke. Scientific Reports, 12. https://doi.org/10.1038/s41598-022-23211-y

Potasso L, Potasso L, Refardt J., Meier C, & Christ-Crain M. (2022). Effect of hyponatremia normalization on osteoblast function in patients with SIAD. European Journal of Endocrinology, 186(1), 1–8. https://doi.org/10.1530/eje-21-0604

Wittermans E, van der Zee PA, Qi H., van de Garde EMW, Blum CA, Christ-Crain M., Gommers D, Grutters JC, Voorn GP, Bos WJW, & Endeman H. (2022). Community-acquired pneumonia subgroups and differential response to corticosteroids: a secondary analysis of controlled studies. ERJ Open Research, 8(1). https://doi.org/10.1183/23120541.00489-2021

Berkmann S, Roethlisberger M, Mueller B, Christ-Crain M., Mariani L., Nitzsche E, & Juengling F. (2021). Selective resection of cushing microadenoma guided by preoperative hybrid 18-fluoroethyl-L-tyrosine and 11-C-methionine PET/MRI. Pituitary, 24(6), 878–886. https://doi.org/10.1007/s11102-021-01160-5

Christ-Crain M, & Gaisl O. (2021). Diabetes insipidus. Presse Medicale (Paris, France : 1983), 50(4), 104093. https://doi.org/10.1016/j.lpm.2021.104093

Sailer C.O., Refardt J, Blum CA, Schnyder I, Molina-Tijeras J.A., Fenske W., Christ-Crain M., & Christ-Crain M. (2021). Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-89505-9

Nobbenhuis R, Nobbenhuis R, Refardt J, Vogt D, Sailer CO, Winzeler B, & Christ-Crain M. (2021). Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers? Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 26(7), 647–655. https://doi.org/10.1080/1354750x.2021.1970808

Raess N., Schuetz P., Cesana-Nigro N., Winzeler B, Urwyler SA, Schaedelin S., Rodondi N, Blum M.R., Briel M., Mueller B, Christ-Crain M., & Blum CA. (2021). Influence of Prednisone on Inflammatory Biomarkers in Community-Acquired Pneumonia: Secondary Analysis of a Randomized Trial. Journal of Clinical Pharmacology, 61(11), 1406–1414. https://doi.org/10.1002/jcph.1914

Heilmann E., Gregoriano C., Annane D., Reinhart K., Bouadma L., Wolff M., Chastre J., Luyt C.-E., Tubach F., Branche A.R., Briel M., Christ-Crain M., Welte T., Corti C., De Jong E., Nijsten M., De Lange D.W., Van Oers J.A.H., Beishuizen A., et al. (2021). Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: A patient-level meta-analysis from randomized controlled trials. Age and Ageing, 50(5), 1546–1556. https://doi.org/10.1093/ageing/afab078

Christ-Crain M, Hoorn EJ, Sherlock M, Thompson CJ, & Wass J. (2021). ENDOCRINOLOGY IN THE TIME OF COVID-19-2021 UPDATES: The management of diabetes insipidus and hyponatraemia. (Patent No. 4). 185(4), Article 4. https://doi.org/10.1530/eje-21-0596

Sailer C.O., Winzeler B, Urwyler SA, Schnyder I., Refardt J, Eckert A., Varghese N., Fassnacht M., Chifu I., Lawson E.A., Verbalis J.G., Fenske W., & Christ-Crain M. (2021). Oxytocin levels in response to pituitary provocation tests in healthy volunteers. European Journal of Endocrinology, 185(3), 355–364. https://doi.org/10.1530/eje-21-0346

Urwyler SA, Lustenberger S, Drummond JR, Soares BS, Vogt DR, Ammer N, Yuen KCJ, Ribeiro-Oliveira A, & Christ-Crain M. (2021). Effects of oral macimorelin on copeptin and anterior pituitary hormones in healthy volunteers. Pituitary, 24(4), 555–563. https://doi.org/10.1007/s11102-021-01132-9

Christ-Crain M, Winzeler B, & Refardt J. (2021). Diagnosis and management of diabetes insipidus for the internist: an update. Journal of Internal Medicine, 290(1), 73–87. https://doi.org/10.1111/joim.13261

Tsagkas C, Schäfer S, Baumgartner A, Müller J, Sinnecker T, Mehling M, van der Stouwe JG, Felder S, Panagiotou A, Potlukova E, Winzeler B, Scholz MC, Timper K, Blackham K, Nickel CH, Christ-Crain M, Bingisser R, Lyrer P, Kappos L, & Yaldizli Ö. (2021). Syndrome of inappropriate antidiuretic hormone secretion and hypothalamic hypocortisolism in neuromyelitis optica. Lancet (London, England), 397(10290), 2194. https://doi.org/10.1016/s0140-6736(21)00986-7

Fischli S, Von Wyl V., Wuillemin W., Von Kanel R., Schütz P, Christ-Crain M., Studer F., Brander L., Schupfer G., Metzger J, & Henzen C. (2021). Impact of adrenal function on Hemostasis/Endothelial function in patients undergoing surgery. Journal of the Endocrine Society, 5(5). https://doi.org/10.1210/jendso/bvab047

Atila C., Sailer C.O., Bassetti S., Tschudin-Sutter S, Bingisser R., Siegemund M, Osswald S, Rentsch K, Rueegg M., Schaerli S., Kuster GM, Twerenbold R, & Christ-Crain M. (2021). Prevalence and outcome of dysnatremia in patients with COVID-19 compared to controls. European Journal of Endocrinology, 184(3), 409–418. https://doi.org/10.1530/eje-20-1374

Stormann S., Schopohl J., Bullmann C., Terkamp C., Christ-Crain M., Finke R., Flitsch J., Kreitschmann-Andermahr I., Luger A., Stalla G., Houchard A., Helbig D., & Petersenn S. (2021). Multicenter, Observational Study of Lanreotide Autogel for the Treatment of Patients with Acromegaly in Routine Clinical Practice in Germany, Austria and Switzerland. Experimental and Clinical Endocrinology and Diabetes, 129(3), 224–233. https://doi.org/10.1055/a-1247-4713

Heilmann E, Gregoriano C, Wirz Y, Luyt CE, Wolff M, Chastre J, Tubach F, Christ-Crain M, Bouadma L, Annane D, Damas P, Kristoffersen KB, Oliveira CF, Stolz D, Tamm M., de Jong E, Reinhart K, Shehabi Y, Verduri A, et al. (2021). Association of kidney function with effectiveness of procalcitonin-guided antibiotic treatment: A patient-level meta-analysis from randomized controlled trials. Clinical Chemistry and Laboratory Medicine, 59(2), 441–453. https://doi.org/10.1515/cclm-2020-0931

Westphal L.P., Schweizer J., Fluri F., De Marchis GM, Christ-Crain M, Luft A.R., & Katan M. (2021). C-Terminal-Pro-Endothelin-1 Adds Incremental Prognostic Value for Risk Stratification After Ischemic Stroke. Frontiers in Neurology, 11. https://doi.org/10.3389/fneur.2020.629151

Christ-Crain M. (2021). Endocrinological diagnosis and replacement therapy for diabetes insipidus (pp. 147–156). Elsevier. https://doi.org/10.1016/b978-0-12-819949-7.00021-4

Ebrahimi, Fahim, Urwyler, Sandrine Andrea, Betz, Matthias Johannes, Christ, Emanuel Remigius, Schuetz, Philipp, Müller, Beat, Donath, Marc Yves, & Christ-Crain, Mirjam. (2021). Effects of interleukin-1 antagonism and corticosteroids on fibroblast growth factor-21 in patients with metabolic syndrome. Scientific Reports, 11(1), 7911. https://doi.org/10.1038/s41598-021-87207-w

Ebrahimi F., Urwyler S.A., Betz M.J., Christ E.R., Schuetz P., Mueller B., Donath M.Y., & Christ-Crain M. (2021). Effects of interleukin-1 antagonism and corticosteroids on fibroblast growth factor-21 in patients with metabolic syndrome. Scientific Reports, 11. https://doi.org/10.1038/s41598-021-87207-w

Potasso, Laura, Refardt, Julie, De Marchis, Gian Marco, Wiencierz, Andrea, Wright, Patrick R, Wagner, Benjamin, Dittrich, Tolga, Polymeris, Alexandros A, Gensicke, Henrik, Bonati, Leo H, & Christ-Crain, Mirjam. (2021). Impact of Sodium Levels on Functional Outcomes in Patients with Stroke - A Swiss Stroke Registry Analysis. The Journal of Clinical Endocrinology and Metabolism, dgab650. https://doi.org/10.1210/clinem/dgab650

Potasso L, Potasso L, Refardt J., Chifu I., Fassnacht M, Fenske W.K., & Christ-Crain M. (2021). Incidence of hyperkalemia during hypertonic saline test for the diagnosis of diabetes insipidus. Endocrine Connections, 10(4), 401–409. https://doi.org/10.1530/ec-20-0531

Refardt J, Pelouto A, Potasso L, Hoorn EJ, & Christ-Crain M. (2021). Hyponatremia Intervention Trial (HIT): Study Protocol of a Randomized, Controlled, Parallel-Group Trial With Blinded Outcome Assessment. Frontiers in Medicine, 8, 729545. https://doi.org/10.3389/fmed.2021.729545

Winzeler, Bettina, Sailer, Clara O, Coynel, David, Zanchi, Davide, Vogt, Deborah R, Urwyler, Sandrine A, Refardt, Julie, & Christ-Crain, Mirjam. (2021). A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia. The Journal of Clinical Investigation, 131(20), e151800. https://doi.org/10.1172/jci151800

Winzeler B, Sailer C.O., Coynel D., Zanchi D., Vogt DR, Urwyler SA, Refardt J, & Christ-Crain M. (2021). A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia. Journal of Clinical Investigation, 131(20). https://doi.org/10.1172/jci151800

Drummond JB, Soares BS, Pedrosa W, Vieira ELM, Teixeira AL, Christ-Crain M, & Ribeiro-Oliveira A Jr. (2020). Copeptin response to hypoglycemic stress is linked to prolactin activation in children. Pituitary, 23(6), 681–690. https://doi.org/10.1007/s11102-020-01076-6

Christ-Crain M. (2020). Copeptin—its value for the diagnosis of polyuria-polydipsia syndrome Copeptin – Stellenwert in der Diagnostik des Polyurie-Polydipsie-Syndroms. Austrian Journal of Clinical Endocrinology and Metabolism, 13(4), 142–150. https://doi.org/10.1007/s41969-020-00106-9

Ebrahimi F, Kutz A, Wagner U, Illigens B, Siepmann T, Schuetz P, Christ-Crain M, Mueller B, Mueller B, & Christ ER. (2020). Excess Mortality Among Hospitalized Patients With Hypopituitarism-A Population-Based, Matched-Cohort Study. The Journal of Clinical Endocrinology and Metabolism, 105(11). https://doi.org/10.1210/clinem/dgaa517

Kutz A, Ebrahimi F, Aghlmandi S, Wagner U, Bromley M, Illigens B, Siepmann T, Schuetz P, Mueller B, Mueller B, & Christ-Crain M. (2020). Risk of Adverse Clinical Outcomes in Hyponatremic Adult Patients Hospitalized for Acute Medical Conditions: A Population-Based Cohort Study. The Journal of Clinical Endocrinology and Metabolism, 105(11), 3428–3436. https://doi.org/10.1210/clinem/dgaa547

Winzeler B, da Conceição I, Refardt J, Sailer CO, Dutilh G, & Christ-Crain M. (2020). Effects of glucagon-like peptide-1 receptor agonists on fluid intake in healthy volunteers. Endocrine, 70(2), 292–298. https://doi.org/10.1007/s12020-020-02394-2

Winzeler B, Morin B, Refardt J, Imber C, Fenske W, Sailer CO, Holbro A, & Christ-Crain M. (2020). Low arginine vasopressin levels in patients with diabetes insipidus are not associated with anaemia. Clinical Endocrinology, 93(4), 456–465. https://doi.org/10.1111/cen.14265

Christ-Crain M. (2020). Diabetes insipidus - An update in diagnosis and management. (Patent No. 5). 34(5), Article 5. https://doi.org/10.1016/j.beem.2020.101470

Refardt J, Winzeler B, & Christ-Crain M. (2020). Diabetes Insipidus: An Update. Endocrinology and Metabolism Clinics of North America, 49(3), 517–531. https://doi.org/10.1016/j.ecl.2020.05.012

Potasso L, Potasso L, Sailer CO, Blum CA, & Christ-Crain M. (2020). Hyponatremia at discharge: A solid risk or accidental findings in community acquired pneumonia - Authors’ reply. 78, 137–138. https://doi.org/10.1016/j.ejim.2020.07.004

Bologna K, Cesana-Nigro N, Refardt J, Imber C, Vogt DR, Christ-Crain M, & Winzeler B. (2020). Effect of Arginine on the Hypothalamic-Pituitary-Adrenal Axis in Individuals With and Without Vasopressin Deficiency. The Journal of Clinical Endocrinology and Metabolism, 105(7). https://doi.org/10.1210/clinem/dgaa157

Christ-Crain M, Hoorn EJ, Sherlock M, Thompson CJ, & Wass JAH. (2020). ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of diabetes insipidus and hyponatraemia. European Journal of Endocrinology, 183(1), G9–G15. https://doi.org/10.1530/eje-20-0338

Popovic M, Ebrahimi F, Urwyler SA, Donath MY, & Christ-Crain M. (2020). The role of IL-1 in the regulation of copeptin in patients with metabolic syndrome. Endocrine Connections, 9(7), 715–723. https://doi.org/10.1530/ec-20-0197

Arnold M., Nakas C, Luft A, Christ-Crain M, Leichtle A, & Katan M. (2020). Independent Prognostic Value of MRproANP (Midregional Proatrial Natriuretic Peptide) Levels in Patients With Stroke Is Unaltered Over Time. Stroke, 51(6), 1873–1875. https://doi.org/10.1161/strokeaha.120.029333