[FG] Puelacher Christian

Research Focus

Cardiovascular & Perioperative Medicine

Area of Research

Perioperative myocardial infarction/injury and perioperative heart failure 

Approved Research Projects

• Basel Incidence, Patient Characteristics, Pathophysiology, and Outcome of Perioperative Myocardial Injury After Non-cardiac Surgery (BASEL-PMI, NCT02573532); prospective pragmatic observational study [2014]
• Reliability of cardiac troponins for the diagnosis of myocardial infarction in the presence of rhabdomyolysis; retrospective cohort study [2016] (CLOSED)
• Impact of implementation of a routine screening and response system for perioperative myocardial injuries/infarctions after non-cardiac surgery (Impact-PMI); retrospective case-cohort study [2019]
• Implementation of a clinical screening and response system for perioperative myocardial infarction/injury after noncardiac surgery (Implement-PMI); prospective multicenter before-after comparison, pilot study [2021]
• Continuous Monitoring of Vital Signs for Improved Phenotyping of Perioperative Myocardial Infarction/Injury after noncardiac surgery in high risk patients (PMI-VITAL); prospective observational study [2022]

Collaborations

National Collaborations

• Implement-PMI: Kantonsspital Olten, Kantonsspital Solothurn, Kantonsspital Luzern, Universitätsspital Genf
• Basel-PMI: Kantonsspital Aarau, Kantonsspital St. Gallen
• Impact-PMI: Kantonsspital Aarau
• USB-Kollaborationen: Anästhesie, Orthopädie
• Kollaborationen: AUTOREGULATE-NONCARDIAC-Studie (Dr. Patrick Wanner)

International Collaborations

• Implement-PMI: Universitätsklinikum Innsbruck, Österreich
• Basel-PMI: INCOR Hospital, Sao Paulo, Brasilien
• MINSS: Michelle Chew, Linköping University, Schweden
• Kollaborationen: A-PoMI (Dr. Jan Larmann, Uniklinikum Heidelberg)

Ongoing Research Projects

• Basel Incidence, Patient Characteristics, Pathophysiology, and Outcome of Perioperative Myocardial Injury After Non-cardiac Surgery (BASEL-PMI, NCT02573532); prospective pragmatic observational study [2014]
• Impact of implementation of a routine screening and response system for perioperative myocardial injuries/infarctions after non-cardiac surgery (Impact-PMI); retrospective case-cohort study [2019]
• Implementation of a clinical screening and response system for perioperative myocardial infarction/injury after noncardiac surgery (Implement-PMI); prospective multicenter before-after comparison, pilot study [2021]
• Continuous Monitoring of Vital Signs for Improved Phenotyping of Perioperative Myocardial Infarction/Injury after noncardiac surgery in high risk patients (PMI-VITAL); prospective observational study [2022]