Faculty of Medicine
Faculty of Medicine
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[FG] Winzeler Bettina

Publications

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Lengsfeld, S. et al. (2024) ‘Effects of the glucagon-like peptide-1 receptor agonist dulaglutide on sexuality in healthy men: a randomised, double-blind, placebo-controlled crossover study’, eBioMedicine, 107. Available at: https://doi.org/10.1016/j.ebiom.2024.105284.

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Atila, Cihan et al. (2024) ‘Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls’, European Journal of Endocrinology, 190, pp. 354–362. Available at: https://doi.org/10.1093/ejendo/lvae040.

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Refardt J et al. (2023) ‘Treatment Effect of the SGLT2 Inhibitor Empagliflozin on Chronic Syndrome of Inappropriate Antidiuresis: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.’, Journal of the American Society of Nephrology : JASN, 34(2), pp. 322–332. Available at: https://doi.org/10.1681/asn.2022050623.

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Baur, Fabienne et al. (2023) ‘Gender differences in weight gain during attempted and successful smoking cessation on dulaglutide treatment: A predefined secondary analysis of a randomised trial’, BMJ Nutrition, Prevention and Health, 6, pp. 301–309. Available at: https://doi.org/10.1136/bmjnph-2023-000781.

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Blum, Claudine A. et al. (2023) ‘Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial’, BMC Pulmonary Medicine, 23. Available at: https://doi.org/10.1186/s12890-023-02794-w.

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Lengsfeld, Sophia et al. (2023) ‘Glucagon-like peptide-1 analogues: a new way to quit smoking? (SKIP)—a structured summary of a study protocol for a randomized controlled study’, Trials, 24. Available at: https://doi.org/10.1186/s13063-023-07164-9.

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Lengsfeld, Sophia et al. (2023) ‘Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial’, eClinicalMedicine, 57. Available at: https://doi.org/10.1016/j.eclinm.2023.101865.

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Potasso, Laura et al. (2023) ‘Chloride and Potassium Assessment Is a Helpful Tool for Differential Diagnosis of Thiazide-Associated Hyponatremia’, Journal of Clinical Endocrinology and Metabolism, 108, pp. 2248–2254. Available at: https://doi.org/10.1210/clinem/dgad133.

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Probst, L. et al. (2023) ‘Effects of dulaglutide on alcohol consumption during smoking cessation’, JCI Insight, 8. Available at: https://doi.org/10.1172/jci.insight.170419.

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Sailer CO et al. (2022) ‘Hypothalamic-pituitary-adrenal axis activity in patients with primary polydipsia compared to healthy controls.’, Clinical endocrinology [Preprint]. Available at: https://doi.org/10.1111/cen.14835.

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Atila C et al. (2022) ‘Central diabetes insipidus from a patient’s perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey’, The Lancet Diabetes and Endocrinology, 10(10), pp. 700–709. Available at: https://doi.org/10.1016/s2213-8587(22)00219-4.

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Winzeler B et al. (2022) ‘Investigating the role of somatic sequencing platforms for phaeochromocytoma and paraganglioma in a large UK cohort.’, Clinical endocrinology, 97(4), pp. 448–459. Available at: https://doi.org/10.1111/cen.14639.

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Atila C et al. (2022) ‘The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults : Data from: Glucacop, Macicop, and CARGO study.’, Pituitary, 25(4), pp. 636–644. Available at: https://doi.org/10.1007/s11102-022-01240-0.

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Christ-Crain M, Refardt J and Winzeler B (2022) ‘Approach to the Patient: ‘Utility of the Copeptin Assay’.’, The Journal of clinical endocrinology and metabolism, 107(6), pp. 1727–1738. Available at: https://doi.org/10.1210/clinem/dgac070.

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Vukajlovic T et al. (2022) ‘Effect of a 3-Week Treatment with GLP-1 Receptor Agonists on Vasoactive Hormones in Euvolemic Participants.’, The Journal of clinical endocrinology and metabolism, 107(6), pp. e2581–e2589. Available at: https://doi.org/10.1210/clinem/dgac063.

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Winzeler B, Challis BG and Casey RT (2021) ‘Precision Medicine in Phaeochromocytoma and Paraganglioma.’, Journal of personalized medicine, 11(11). Available at: https://doi.org/10.3390/jpm11111239.

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Nobbenhuis R et al. (2021) ‘Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers?’, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 26(7), pp. 647–655. Available at: https://doi.org/10.1080/1354750x.2021.1970808.

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Raess N. et al. (2021) ‘Influence of Prednisone on Inflammatory Biomarkers in Community-Acquired Pneumonia: Secondary Analysis of a Randomized Trial’, Journal of Clinical Pharmacology, 61(11), pp. 1406–1414. Available at: https://doi.org/10.1002/jcph.1914.

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Sailer C.O. et al. (2021) ‘Oxytocin levels in response to pituitary provocation tests in healthy volunteers.’, European journal of endocrinology, 185(3), pp. 355–364. Available at: https://doi.org/10.1530/eje-21-0346.

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Christ-Crain M, Winzeler B and Refardt J (2021) ‘Diagnosis and management of diabetes insipidus for the internist: an update.’, Journal of internal medicine, 290(1), pp. 73–87. Available at: https://doi.org/10.1111/joim.13261.

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Tsagkas C et al. (2021) ‘Syndrome of inappropriate antidiuretic hormone secretion and hypothalamic hypocortisolism in neuromyelitis optica.’, Lancet (London, England), 397(10290), p. 2194. Available at: https://doi.org/10.1016/s0140-6736(21)00986-7.

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Winzeler B et al. (2021) ‘A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia’, Journal of Clinical Investigation, 131(20). Available at: https://doi.org/10.1172/jci151800.

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Huhn E.A. et al. (2020) ‘Effectiveness of real-time continuous glucose monitoring to improve glycaemic control and pregnancy outcome in patients with gestational diabetes mellitus: A study protocol for a randomised controlled trial’, BMJ Open, 10(11). Available at: https://doi.org/10.1136/bmjopen-2020-040498.

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Winzeler B et al. (2020) ‘Effects of glucagon-like peptide-1 receptor agonists on fluid intake in healthy volunteers.’, Endocrine, 70(2), pp. 292–298. Available at: https://doi.org/10.1007/s12020-020-02394-2.

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Winzeler B et al. (2020) ‘Low arginine vasopressin levels in patients with diabetes insipidus are not associated with anaemia.’, Clinical endocrinology, 93(4), pp. 456–465. Available at: https://doi.org/10.1111/cen.14265.

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Refardt J, Winzeler B and Christ-Crain M (2020) ‘Diabetes Insipidus: An Update.’, Endocrinology and metabolism clinics of North America, 49(3), pp. 517–531. Available at: https://doi.org/10.1016/j.ecl.2020.05.012.

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Bologna K et al. (2020) ‘Effect of Arginine on the Hypothalamic-Pituitary-Adrenal Axis in Individuals With and Without Vasopressin Deficiency.’, The Journal of clinical endocrinology and metabolism, 105(7). Available at: https://doi.org/10.1210/clinem/dgaa157.

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Refardt J et al. (2020) ‘A Randomized Trial of Empagliflozin to Increase Plasma Sodium Levels in Patients with the Syndrome of Inappropriate Antidiuresis.’, Journal of the American Society of Nephrology : JASN, 31(3), pp. 615–624. Available at: https://doi.org/10.1681/asn.2019090944.

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Winzeler B and Christ-Crain M (2020) ‘Use of copeptin in the diagnosis of polyuria-polydipsia syndrome - Authors” reply.’, 395(10220). Available at: https://doi.org/10.1016/s0140-6736(19)32964-2.

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Winzeler B et al. (2020) ‘Copeptin is not useful as a marker of malignant disease in the syndrome of inappropriate antidiuresis.’, Endocrine connections, 9(1), pp. 20–27. Available at: https://doi.org/10.1530/ec-19-0431.

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Winzeler B et al. (2019) ‘Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a prospective diagnostic study.’, Lancet (London, England), 394(10198), pp. 587–595. Available at: https://doi.org/10.1016/s0140-6736(19)31255-3.

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Chtioui H et al. (2019) ‘High concentration of plasma methoxytyramine: dopamine-producing tumour or Parkinson’s disease therapy?’, Annals of clinical biochemistry, 56(4), pp. 466–471. Available at: https://doi.org/10.1177/0004563219835263.

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Blum, Claudine A. et al. (2019) ‘Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial’, Clinical endocrinology, 91(3), pp. 374–382. Available at: https://doi.org/10.1111/cen.13907.

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Popovic, Milica et al. (2019) ‘Estimation of treatment allocation in a randomised, double-blinded, placebo-controlled trial’, Swiss medical weekly, 149, p. w20114. Available at: https://doi.org/10.4414/smw.2019.20114.

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Refardt, Julie et al. (2019) ‘The challenges of sodium measurements - indirect versus direct ion selective method’, European journal of endocrinology, 181(2), pp. 193–199. Available at: https://doi.org/10.1530/eje-19-0101.

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Refardt, Julie, Winzeler, Bettina and Christ-Crain, Mirjam (2019) ‘Copeptin and its role in the diagnosis of diabetes insipidus and the syndrome of inappropriate antidiuresis’, Clinical endocrinology, 91(1), pp. 22–32. Available at: https://doi.org/10.1111/cen.13991.

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Sailer, Clara O. et al. (2019) ‘Influence of Outdoor Temperature and Relative Humidity on Incidence and Etiology of Hyponatremia’, The Journal of clinical endocrinology and metabolism, 104(4), pp. 1304–1312. Available at: https://doi.org/10.1210/jc.2018-01507.

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Winzeler B et al. (2019) ‘Effects of Glucagon-Like Peptide-1 Receptor Agonists on Hypothalamic-Pituitary-Adrenal Axis in Healthy Volunteers.’, The Journal of clinical endocrinology and metabolism, 104(1), pp. 202–208. Available at: https://doi.org/10.1210/jc.2018-01420.

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Fenske W et al. (2018) ‘A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus.’, The New England journal of medicine, 379(5), pp. 428–439. Available at: https://doi.org/10.1056/nejmoa1803760.

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Nigro N et al. (2018) ‘Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the ‘Co-MED study’.’, Critical care (London, England), 22(1), p. 33. Available at: https://doi.org/10.1186/s13054-018-1955-7.

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Refardt, Julie et al. (2018) ‘FGF-21 levels in polyuria-polydipsia syndrome’, Endocrine connections, 7(12), pp. 1501–1506. Available at: https://doi.org/10.1530/ec-18-0469.

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Sailer CO, Winzeler B and Christ-Crain M (2018) ‘Reply to comment on: Sailer CO, et al. Primary polydipsia in the medical and psychiatric patient: characteristics, complications and therapy.’, 148. Available at: https://doi.org/10.4414/smw.2018.14609.

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Winzeler B.F. et al. (2018) ‘Hypothyroidism, subclinical’. Elsevier, pp. 630–635. Available at: https://doi.org/10.1016/b978-0-12-801238-3.04162-3.

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Sailer CO et al. (2017) ‘Characteristics and outcomes of patients with profound hyponatraemia due to primary polydipsia.’, 87(5). Available at: https://doi.org/10.1111/cen.13384.

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Refardt J et al. (2017) ‘Artificial Syndrome of Inappropriate Antidiuresis Model as Potential Use for Diagnostic and Therapeutic Strategies.’, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 23.08.2017, 49(9), pp. 673–679. Available at: https://doi.org/10.1055/s-0043-113450.

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Huhn, Evelyn A et al. (2017) ‘Fourfold increase in prevalence of gestational diabetes mellitus after adoption of the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.’, Journal of perinatal medicine, 45(3), pp. 359–366. Available at: https://doi.org/10.1515/jpm-2016-0099.

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Blum, Claudine Angela et al. (2017) ‘Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study’, Journal of Headache and Pain, 18(1), p. 21. Available at: https://doi.org/10.1186/s10194-017-0733-2.

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Nigro, Nicole et al. (2017) ‘Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: “The Co-MED Study”’, Clinical Endocrinology, 86(3), pp. 456–462. Available at: https://doi.org/10.1111/cen.13243.

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Refardt J et al. (2017) ‘Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis.’, International journal of endocrinology, 2017, p. 7815690. Available at: https://doi.org/10.1155/2017/7815690.

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Sailer C, Winzeler B and Christ-Crain M (2017) ‘Primary polydipsia in the medical and psychiatric patient: characteristics, complications and therapy.’, Swiss medical weekly, 147, p. w14514. Available at: https://doi.org/10.4414/smw.2017.14514.

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Winzeler, Bettina et al. (2016) ‘Long-term outcome of profound hyponatremia: a prospective 12 months follow-up study’, European Journal of Endocrinology, 175(6), pp. 499–507. Available at: https://doi.org/10.1530/eje-16-0500.

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Winzeler, B. et al. (2016) ‘Predictors of nonresponse to fluid restriction in hyponatraemia due to the syndrome of inappropriate antidiuresis’, Journal of Internal Medicine, 280(6), pp. 609–617. Available at: https://doi.org/10.1111/joim.12532.

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Wirz, Sebastian A. et al. (2016) ‘Pathogen- and antibiotic-specific effects of prednisone in community-acquired pneumonia’, European Respiratory Journal, 48(4), pp. 1150–1159. Available at: https://doi.org/10.1183/13993003.00474-2016.

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Winzeler B, Dickenmann M and Jehle AW (2015) ‘Diabetische Nephropathie und Anpassung der antidiabetischen Therapie bei Niereninsuffizienz.’, Therapeutische Umschau. Revue therapeutique, 72(3), pp. 149–55. Available at: https://doi.org/10.1024/0040-5930/a000658.

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Blum CA, Nigro N. et al. (2015) ‘Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial’, Lancet, 385(9977), pp. 1511–8. Available at: https://doi.org/10.1016/s0140-6736(14)62447-8.

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Nigro, N. et al. (2015) ‘Mid-regional pro-atrial natriuretic peptide and the assessment of volaemic status and differential diagnosis of profound hyponatraemia’, Journal of Internal Medicine, 278(1), pp. 29–37. Available at: https://doi.org/10.1111/joim.12332.

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Nigro, N. et al. (2015) ‘Symptoms and characteristics of individuals with profound hyponatremia: a prospective multicenter observational study’, Journal of the American Geriatrics Society, 63(3), pp. 470–5. Available at: https://doi.org/10.1111/jgs.13325.

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Winzeler, B. et al. (2015) ‘Postoperative Copeptin Concentration Predicts Diabetes Insipidus After Pituitary Surgery’, Journal of Clinical Endocrinology and Metabolism, 100(6), pp. 2275–82. Available at: https://doi.org/10.1210/jc.2014-4527.

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Winzeler,BF et al. (2015) ‘Hypothyroidism Subclinical: Encyclopedia of Endocrinology and Endocrine Diseases’, pp. B978–012–201238–3.0416–3.

Blum, C. A. et al. (2014) ‘Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial’, Trials, 15, p. 257. Available at: https://doi.org/10.1186/1745-6215-15-257.

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Steveling, Esther H., Winzeler, Bettina and Bircher, Andreas J. (2014) ‘Systemic allergic reaction to the GLP-1 receptor agonist exenatide’, The Journal of Pharmacy Technology, 30(5), pp. 182–186. Available at: https://doi.org/10.1177/8755122514539462.

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Winzeler B et al. (2013) ‘Hyponatriämie als Zufallsbefund.’, Therapeutische Umschau. Revue therapeutique, 70(5), pp. 289–95. Available at: https://doi.org/10.1024/0040-5930/a000405.

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Winzeler BF and Christ-Crain M (2012) ‘[Hormones as biomarkers for diagnosis and prognosis].’, Praxis, 101(4), pp. 251–7. Available at: https://doi.org/10.1024/1661-8157/a000837.

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