Faculty of Medicine
Faculty of Medicine
UNIverse - Public Research Portal

[FG] De Marchis Gian Marco

Research Group Gian Marco De Marchis

Acute cerebrovascular diseases and their management with focus on endovascular treatment and intravenous thrombolysis. Secondary Prevention of Stroke: randomized clinical trials, dyslipidemia, ideal time to start anticoagulant therapy after a stroke. Cohort studies on novel blood markers. Copeptin as first blood marker for prognosis after stroke and TIA. Prehospital stroke care networks to reduce delays. Safety and effectiveness of fast-track vs. open-end hospitalizations.


Approved Research Projects

  • AtheroGEnic LipoprotEinS in Ischemic Stroke - The AGELESS Study (Sponsor: Schweizerischer Nationalfond)
  • Serum Neurofilaments Light Chain in Acute Ischemic Stroke and Transient Ischemic Attack (cohort study).
  • Endovascular Treatment versus Best Medical Treatment for Ischemic Stroke with Large Vessel Occlusion in the 6–24 Hour Window among Non- DAWN-Non-DEFUSE Patients (Study based on the Swiss Stroke Registry)
  • Apolipoprotein (B) and Lipoprotein(a) in Patients with Acute Ischemic Stroke 


Collaborations

National Collaborations

  • Biomarker Signature of Stroke Aetiology Study: The BIOSIGNAL-Study (NCT02274727)
  • Midregion Proatrial Natriuretic Peptide to Guide Secondary Stroke Prevention (ongoing, steering committee member, NCT03961334)
  • Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN, NCT03148457)
  • Swiss Atrial Fibrillation Cohort (SWISS AF)

International Collaborations

  • Tenecteplase in Wake-Up Stroke Trial (ongoing, steering committee member, NCT03181360)
  • PACIFIC-STROKE (ongoing, steering committee member, NCT04304508)


Ongoing Research Projects

  • AtheroGEnic LipoprotEinS in Ischemic Stroke - The AGELESS Study (Sponsor: Schweizerischer Nationalfond)
  • Endovascular Treatment versus Best Medical Treatment for Ischemic Stroke with Large Vessel Occlusion in the 6–24 Hour Window among Non- DAWN-Non-DEFUSE Patients (Study based on the Swiss Stroke Registry)
  • Apolipoprotein (B) and Lipoprotein(a) in Patients with Acute Ischemic Stroke 


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