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[FG] Ruppen Wilhelm

Publications

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Lehmann, Anja et al. (2025) ‘Epidural dexamethasone-21-palmitate for spinal stenosis-related pain: a retrospective cohort study using patient-reported outcome data’, Swiss Medical Weekly, 155(4), p. 4100. Available at: https://doi.org/10.57187/s.4100.

Daneffel, Luana et al. (2025) ‘Preferential C-nociceptor stimulation facilitates peripheral axon reflex flare, but not secondary mechanical hyperalgesia’, Frontiers in Pain Research, 6. Available at: https://doi.org/10.3389/fpain.2025.1556429.

Daneffel, Luana et al. (2025) ‘Preferential C-nociceptor stimulation facilitates peripheral axon reflex flare, but not secondary mechanical hyperalgesia’, Frontiers in Pain Research, 6. Available at: https://doi.org/10.3389/fpain.2025.1556429.

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Lehmann, Anja et al. (2025) ‘Epidural dexamethasone-21-palmitate for spinal stenosis-related pain: a retrospective cohort study using patient-reported outcome data’, Swiss Medical Weekly, 155. Available at: https://doi.org/10.57187/s.4100.

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Hojski, Aljaz et al. (2024) ‘Perioperative intravenous lidocaine in thoracoscopic surgery for improved postoperative pain control: a randomized, placebo-controlled, double-blind, superiority trial’, Journal of Thoracic Disease, 16(3), pp. 1923–1932. Available at: https://doi.org/10.21037/jtd-23-1438.

de Leeuw, Matthijs et al. (2024) ‘Boosting open-label placebo effects in acute induced pain in healthy adults (BOLPAP-study): study protocol of a randomized controlled trial’, Frontiers in Medicine, 11. Available at: https://doi.org/10.3389/fmed.2024.1238878.

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Striebel, Julia, Ruppen, Wilhelm and Schneider, Tobias (2023) ‘Simultaneous application of lidocaine and ketamine during ambulatory infusion therapy: a retrospective analysis’, Pain Management. 18.10.2023, 13(9), pp. 539–553. Available at: https://doi.org/10.2217/pmt-2023-0037.

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Schneider T et al. (2023) ‘Optimized Electrical Stimulation of C-Nociceptors in Humans Based on the Chronaxie of Porcine C-Fibers’, Journal of Pain, 24(6), pp. 957–969. Available at: https://doi.org/10.1016/j.jpain.2023.01.009.

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Dieterle M et al. (2022) ‘Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II)’, Pain, 163(10), pp. 1919–1928. Available at: https://doi.org/10.1097/j.pain.0000000000002591.

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Schneider T et al. (2022) ‘Analgesic benefit of metamizole and ibuprofen vs. either medication alone: a randomized clinical trial’, Minerva Anestesiologica, 88(6), pp. 448–456. Available at: https://doi.org/10.23736/S0375-9393.22.16346-7.

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Schneider T et al. (2022) ‘Pain response to cannabidiol in induced acute nociceptive pain, allodynia, and hyperalgesia by using a model mimicking acute pain in healthy adults in a randomized trial (CANAB I)’, Pain, 163(1), pp. E62–E71. Available at: https://doi.org/10.1097/j.pain.0000000000002310.

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Pascal Gerster and Wilhelm Ruppen (2022) ‘Schmerzmedizin in der Geriatrie’, der informierte Arzt [Preprint], (September 2022).

Sezer, Dilan et al. (2021) ‘Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial’, Frontiers in medicine, 8, p. 687398. Available at: https://doi.org/10.3389/fmed.2021.687398.

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Tobias Schneider (2021) ‘Pharmakotherapie von Schmerzen - In drei Stufen zum Ziel’, Doctors today, 1(2), pp. 16–19. Available at: https://doctors.today/a/pharmakotherapie-von-schmerzen-in-drei-stufen-zum-ziel-2296207.

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Schneider T et al. (2020) ‘Pain Response to Open Label Placebo in Induced Acute Pain in Healthy Adult Males’, Anesthesiology, 132(3), pp. 571–580. Available at: https://doi.org/10.1097/ALN.0000000000003076.

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Ruppen W. and Schneider T. (2020) ‘Modern pain treatment in oncology Moderne Schmerztherapie in der Onkologie’, Onkologe, 26(2), pp. 139–143. Available at: https://doi.org/10.1007/s00761-019-00676-7.

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Brunkert, Thekla et al. (2020) ‘A Contextual Analysis to Explore Barriers and Facilitators of Pain Management in Swiss Nursing Homes’, Journal of Nursing Scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing, 52(1), pp. 14–22. Available at: https://doi.org/10.1111/jnu.12508.

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Ruppen W and Schneider T (2020) ‘[Opioid crisis: What now? A pain specialist’s point of view].’, Therapeutische Umschau. Revue therapeutique, 77(1), pp. 3–9. Available at: https://doi.org/10.1024/0040-5930/a001143.

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Ruppen W and Schneider T (2020) ‘Moderne Schmerztherapie in der Onkologie’, Der Onkologe, 26(2), pp. 139–143.

Mauermann E et al. (2019) ‘Association between intra-operative fentanyl dosing and postoperative nausea/vomiting and pain: A prospective cohort study’, European Journal of Anaesthesiology, 36(11), pp. 871–880. Available at: https://doi.org/10.1097/EJA.0000000000001081.

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Schneider T et al. (2019) ‘Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children’s Hospital Basel - a retrospective study’, Swiss medical weekly, 149, p. w20073. Available at: https://doi.org/10.4414/smw.2019.20073.

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Brunkert, Thekla et al. (2019) ‘A theory-based hybrid II implementation intervention to improve pain management in Swiss nursing homes: A mixed-methods study protocol’, Journal of Advanced Nursing, 75(2), pp. 432–442. Available at: https://doi.org/10.1111/jan.13817.

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Brunkert, Thekla et al. (2019) ‘Pain Management in Nursing Home Residents: Findings from a Pilot Effectiveness-Implementation Study’, Journal of the American Geriatrics Society, 67(12), pp. 2574–2580. Available at: https://doi.org/10.1111/jgs.16148.

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PD Dr. med Jan Gärtner, Dr,. med Tobias Schneider and Dr. med. Sandra Eckstein (2019) ‘Medikamentöse Tumorschmerztherapie’, Swiss Medical Forum, 5-6(19), pp. 83–90.

Schneider,Tobias and Ruppen,Wilhelm (2018) ‘Refraktäre Schmerzen bei Tumorpatienten: Interdisziplinäre Zusammenarbeit für eine bestmögliche multimodale Schmerztherapie’, info@onkologie, 8(5), pp. 30–32. Available at: https://www.google.ch/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=2ahUKEwjPxdDFxPTfAhXvkIsKHW07AZ4QFjAAegQICRAC&url=https%3A%2F%2Fwww.medinfo-verlag.ch%2Ffiles%2Fdownload%2F3dd585905cdc642&usg=AOvVaw2XcNISyBB5ZM2uzSYXcbVX.

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Schneider,Tobias and Ruppen,Wilhelm (2018) ‘Tumorschmerzen: Büchse der Pandora – Chancen und Gefahren der Schmerztherapie.’, Info Onkologie & Hämatologie, 6(4), pp. 13–15.

Tobias Schneider and Wilhelm Ruppen (2018) ‘Büchse der Pandora - Chancen und Gefahren der Schmerztherapie’, OnFo Onkologie & Hämatologie, 6(4), pp. 2–5.

Tobias Schneider and Wilhelm Ruppen (2018) ‘Interdiszipliäre Zusammenarbeit für eine bestmögliche multimodale Schmerztherapie’, Info@onkologie, 5, pp. 30–32. Available at: https://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwiy_dr0p8H7AhXc7rsIHRzWAUwQFnoECBQQAQ&url=https%3A%2F%2Fwww.tellmed.ch%2Finclude_php%2Fpreviewdoc.php%3Ffile_id%3D18256&usg=AOvVaw39lezFUeHmR8-0swJoaloQ.

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Mauermann E, Ruppen W and Bandschapp O (2017) ‘Different protocols used today to achieve total opioid-free general anesthesia without locoregional blocks’, Best Practice and Research: Clinical Anaesthesiology, 31(4), pp. 533–545. Available at: https://doi.org/10.1016/j.bpa.2017.11.003.

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Mauermann E et al. (2017) ‘Time course of copeptin during a model of experimental pain and hyperalgesia: A randomised volunteer crossover trial’, European Journal of Anaesthesiology, 34(5), pp. 306–314. Available at: https://doi.org/10.1097/EJA.0000000000000592.

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Briner A and Schneider T (2017) ‘Cannabinoide in der Schmerztherapie.’, Therapeutische Umschau. Revue therapeutique, 74(5), pp. 261–266. Available at: https://doi.org/10.1024/0040-5930/a000913.

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Freiermuth D, Aeschbach A and Ruppen W (2017) ‘Das komplexe regionale Schmerzsyndrom. Epidemiologie, Pathophysiologie und Behandlung. Ein Update.’, Therapeutische Umschau. Revue therapeutique, 74(5), pp. 223–231. Available at: https://doi.org/10.1024/0040-5930/a000908.

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Oppliger M, Mauermann E and Ruppen W (2017) ‘Reply to: Are transdermal opioids contraindicated in patients at risk of suicide?’, European Journal of Anaesthesiology. Lippincott Williams and Wilkinsagents@lww.com, 34(1). Available at: https://doi.org/10.1097/EJA.0000000000000483.

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Ruppen W (2017) ‘Der chronische Schmerz und seine Facetten: faszinierend und erschreckend zugleich.’, Therapeutische Umschau. Revue therapeutique, 74(5), pp. 213–214. Available at: https://doi.org/10.1024/0040-5930/a000906.

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Schneider T and Ruppen W (2017) ‘Opiate – Fluch oder Segen? – Eine aktuelle Übersicht.’, Therapeutische Umschau. Revue therapeutique, 74(5), pp. 277–283. Available at: https://doi.org/10.1024/0040-5930/a000915.

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Kirsch,Monika, Ries Gisler,Tobias and Ruppen,Wilhelm (2017) ‘Wenn Schmerzen nicht zu bändigen sind – die intrathekale Schmerztherapie bei Therapierefraktärem Tumorschmerz.’, Anästhesie Journal, 3, pp. 22–25.

Kirsch,Monika, Ries Gisler,Tobias and Ruppen,Wilhelm (2017) ‘Rein oder raus – wie wirksam ist die Zugabe von Ketamin in eine Opioid-PCA-Pumpe?’, Anästhesie Journal, 3, pp. 22–25.

Oppliger M, Mauermann E and Ruppen W (2016) ‘Are transdermal opioids contraindicated in patients at risk of suicide?: An underappreciated problem’, European Journal of Anaesthesiology, 33(8), pp. 604–605. Available at: https://doi.org/10.1097/EJA.0000000000000393.

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Mauermann E et al. (2016) ‘Does Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?: A Double-blind, Randomized, Crossover Trial’, Anesthesiology, 124(2), pp. 453–463. Available at: https://doi.org/10.1097/ALN.0000000000000976.

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Bandschapp,O et al. (2016) ‘Utility of a standardized, multidisciplinary rehabilitation program for chronic low back pain’, 1, pp. 1–8.

Kirsch,Monika and Ruppen,Wilhelm (2016) ‘Interventionelle Schmerztherapie, Schmerzlinderung bei hochkomplexen Schmerzen in der Onkologie’, Onkologiepflege, 4(4), pp. 10–13.

Freiermuth D et al. (2015) ‘Correlation of 99mTc-DPD SPECT/CT Scan Findings and Diagnostic Blockades of Lumbar Medial Branches in Patients with Unspecific Low Back Pain in a Randomized-Controlled Trial’, Pain Medicine (United States), 16(10), pp. 1916–1922. Available at: https://doi.org/10.1111/pme.12841.

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Nadine Donnerstag et al. (2015) Severe opioid withdrawal syndrome after a single dose of nalmefene, European Journal of Clinical Pharmacology. 8. Springer Verlagservice@springer.de, pp. 1025–1026. Available at: https://doi.org/10.1007/s00228-015-1884-1.

Klatt E. et al. (2015) ‘Intra- and postoperative intravenous ketamine does not prevent chronic pain: A systematic review and meta-analysis’, Scandinavian Journal of Pain, 7, pp. 42–54. Available at: https://doi.org/10.1016/j.sjpain.2014.12.005.

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Riediger C et al. (2015) ‘The analgesic effect of combined treatment with intranasal S-ketamine and intranasal midazolam compared with morphine patient-controlled analgesia in spinal surgery patients: A pilot study’, Journal of Pain Research, 8, pp. 87–94. Available at: https://doi.org/10.2147/JPR.S75928.

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Schneider T et al. (2015) ‘Thrombin generation and rotational thromboelastometry in the healthy adult population’, Hamostaseologie, 35(2), pp. 181–186. Available at: https://doi.org/10.5482/hamo-14-08-0033.

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Ruppen,Wilhelm (2014) ‘Neues und Bekanntes aus der interventionellen Schmerztherapie’, Psychiatrie und Neurologie, 16(5), pp. 20–24. Available at: http://www.tellmed.ch/tellmed/Fachliteratur/Psychiatrie/Neurologie/Psychiatrie_Neurologie_Archiv.php.

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Pouskoulas CD, Taub E and Ruppen W (2013) ‘Successful treatment of post-dural-puncture headache with surgical dura repair two years after spinal anesthesia’, Cephalalgia, 33(15), pp. 1269–1271. Available at: https://doi.org/10.1177/0333102413490348.

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Kahmann I.V. et al. (2012) ‘Perioperative pharmacotherapy. What should be considered for the perioperative drug management? Perioperative pharmakotherapie. Was soll zum perioperativen medikamentenmanagement beachtet werden?’, Internistische Praxis, 52(4), pp. 841–860.

Pouskoulas CD, Aeschbach A and Ruppen W (2012) ‘[Anaesthesia and pain therapy: perioperative management of patients with complex regional pain syndrome].’, Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. 12.12.2012, 47(11-12), pp. 688–95. Available at: https://doi.org/10.1055/s-0032-1331365.

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Bolliger, D et al. (2012) ‘The influence of pre-admission hypoglycaemic therapy on cardiac morbidity and mortality in type 2 diabetic patients undergoing major non-cardiac surgery: a prospective observational study*’, Anaesthesia, 67(2), pp. 149–57. Available at: https://doi.org/10.1111/j.1365-2044.2011.06963.x.

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Kaufmann,M. et al. (2012) ‘Anästhesie’, in Siewert JR, Stein HJ (ed.) Chirurgie. 9 edn. Springer-Verlag (Chirurgie), pp. 127–148. Available at: https://doi.org/10.1007/978-3-642-11331-4.

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Vogel Kahmann,I. et al. (2012) ‘Perioperative Pharmakotherapie. Was soll zum perioperativen Medikamentenmanagement beachtet werden?’, Arzneimittel-, Therapie-Kritik & Medizin und Umwelt, 44(4), p. 309.

Plagge H et al. (2011) ‘Dose calculation in opioid rotation: Electronic calculator vs. manual calculation’, International Journal of Clinical Pharmacy. 13.01.2011, 33(1), pp. 25–32. Available at: https://doi.org/10.1007/s11096-010-9464-z.

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Bandschapp,O et al. (2011) ‘Presenting data versus predictions as basic scientific information: Target-controlled infusions versus microgram per kilogram per minutes [2]’, Anesthesiology, 114(3), pp. 721–722. Available at: https://doi.org/10.1097/ALN.0b013e3182096be5.

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Bandschapp, Oliver et al. (2011) ‘Tropisetron blocks analgesic action of acetaminophen : a human pain model study’, Pain, 152(6), pp. 1304–10. Available at: https://doi.org/10.1016/j.pain.2011.02.003.

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Vogel Kahmann, I et al. (2011) ‘[Perioperative management of long-term medication]’, Der Internist, 52(1), pp. 89–98. Available at: https://doi.org/10.1007/s00108-010-2755-6.

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Ruppen W., Bandschapp O. and Urwyler A. (2010) ‘Language difficulties in outpatients and their impact on a chronic pain unit in northwest Switzerland’, Swiss Medical Weekly, 140(17-18), pp. 260–264.

Ruppen W, Bandschapp O and Urwyler A (2010) ‘Language difficulties in outpatients and their impact on a chronic pain unit in northwest Switzerland’, Swiss Medical Weekly, 140(17-18), pp. 260–264. Available at: https://doi.org/10.4414/smw.2010.12816.

Ruppen,W and Aeschbach,A (2010) ‘Opiates in the practice: An effective instrument for persistent pain Opiate in der praxis: Ein wirksames instrument bei anhaltenden schmerzen’, Praxis. Verlag Hans Huber AGcustomerservice@hogrefe-publishing.com, 99(5). Available at: https://doi.org/10.1024/1661-8157/a000049.

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Bandschapp, Oliver et al. (2010) ‘Analgesic and antihyperalgesic properties of propofol in a human pain model’, Anesthesiology, 113(2), pp. 421–8. Available at: https://doi.org/10.1097/aln.0b013e3181e33ac8.

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Bruggisser,M et al. (2010) ‘AV-Block III und mechanische Reanimation nach Anästhesieeinleitung mit Propofol und Fentanyl. Eine Kasuistik’, Swiss Medical Forum, 10(2), pp. 657–658. Available at: http://www.medicalforum.ch/docs/smf/archiv/de/2010/2010-38/2010-38-181.pdf.

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Aprili, Daniel et al. (2009) ‘Serious complications associated with external intrathecal catheters used in cancer pain patients : a systematic review and meta-analysis’, Anesthesiology, 111(6), pp. 1346–55. Available at: https://doi.org/10.1097/aln.0b013e3181bfab9a.

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Ruppen, W et al. (2009) ‘Bupivacaine concentrations in the lumbar cerebrospinal fluid of patients during spinal anaesthesia’, BJA : British journal of anaesthesia, 102(6), pp. 832–8. Available at: https://doi.org/10.1093/bja/aep049.

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Steiner, L A et al. (2009) ‘Bupivacaine concentrations in lumbar cerebrospinal fluid in patients with failed spinal anaesthesia’, BJA : British journal of anaesthesia, 102(6), pp. 839–44. Available at: https://doi.org/10.1093/bja/aep050.

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Ruppen, W et al. (2008) ‘Neurological symptoms after cervical transforaminal injection with steroids in a patient with hypoplasia of the vertebral artery’, Acta anaesthesiologica Scandinavica, 52(1), pp. 165–6. Available at: https://doi.org/10.1111/j.1399-6576.2007.01484.x.

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Ruppen W et al. (2007) ‘Infection rates associated with epidural indwelling catheters for seven days or longer: Systematic review and meta-analysis’, BMC Palliative Care. 04.04.2007, 6, p. 3. Available at: https://doi.org/10.1186/1472-684X-6-3.

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Ruppen W, Urwyler A and Seeberger M (2007) ‘Self-limiting epidural haematoma imitating an incorrectly placed epidural catheter [4]’, Acta Anaesthesiologica Scandinavica, 51(4). Available at: https://doi.org/10.1111/j.1399-6576.2007.01264.x.

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Ruppen W et al. (2006) ‘Incidence of epidural haematoma and neurological injury in cardiovascular patients with epidural analgesia/anaesthesia: Systematic review and meta-analysis’, BMC Anesthesiology. 12.09.2006, 6, p. 10. Available at: https://doi.org/10.1186/1471-2253-6-10.

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Ruppen W. et al. (2006) ‘Incidence of epidural hematoma, infection, and neurologic injury in obstetric patients with epidural analgesia/anesthesia’, Anesthesiology, 105(2), pp. 394–399. Available at: https://doi.org/10.1097/00000542-200608000-00023.

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Ruppen, Wilhelm et al. (2006) ‘Incidence of epidural hematoma, infection, and neurologic injury in obstetric patients with epidural analgesia/anesthesia’, ANESTHESIOLOGY, 105, pp. 394–399.

Ruppen W et al. (2006) ‘Electrical shock in the operating theatre: What to do? [12]’, Acta Anaesthesiologica Scandinavica, 50(5). Available at: https://doi.org/10.1111/j.1399-6576.2006.00950.x.

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Urwyler,A. and Ruppen,W. (2006) ‘Effects of Halogenated Agents on Receptors and Ion Channels’, pp. 113–116.

Ruppen W and Schüpfer GK (2005) ‘Exacerbation of carpal tunnel syndrome under treatment with valdecoxib [4]’, Anesthesia and Analgesia, 100(4). Available at: https://doi.org/10.1213/01.ANE.0000146669.40220.54.

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Ruppen W et al. (2005) ‘Propofol and questionable lack of sedation [2]’, Acta Anaesthesiologica Scandinavica, 49(3). Available at: https://doi.org/10.1111/j.1399-6576.2005.00629.x.

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Jöhr M et al. (2003) ‘Congenital laryngotracheo-oesophageal cleft: Successful ventilation with the Laryngeal Mask Airway™’, Paediatric Anaesthesia, 13(1), pp. 68–71. Available at: https://doi.org/10.1046/j.1460-9592.2003.00955.x.

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Ruppen, W et al. (2003) ‘Cardiac arrest in an infant with congenital adrenal hyperplasia’, ACTA ANAESTHESIOLOGICA SCANDINAVICA, 47, pp. 104–105.

Ruppen,Wilhelm et al. (2002) ‘Tracheal rupture in a 12 year-old-child: a possible complication of tracheal intubation?’, Paediatr Anaesth, 12(2), pp. 465–6.

Ruppen,W. et al. (2000) ‘Emergency cricothyroidotomy in upper airway obstruction in adult epiglottitis’, Notarzt, 16(4), pp. 138–140. Available at: https://doi.org/10.1055/s-2000-3805.

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