Molecular and Systems Toxicology (Odermatt)

Verouti, S. et al. (2024) ‘Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity’, Pflügers Archiv - European Journal of Physiology [Preprint]. Available at: https://doi.org/10.1007/s00424-024-03014-y.

Gómez, C. et al. (2024) ‘Identification of a human blood biomarker of pharmacological 11β-hydroxysteroid dehydrogenase 1 inhibition’, British Journal of Pharmacology, 181(5), pp. 698–711. Available at: https://doi.org/10.1111/bph.16251.

Kolesnyk, Serhii et al. (2023) ‘A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies’, Toxicology in Vitro, 93, p. 105706. Available at: https://doi.org/10.1016/j.tiv.2023.105706.

Jäger, Marie-Christin et al. (2023) ‘Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase’, Toxicology and Applied Pharmacology, 475, p. 116638. Available at: https://doi.org/10.1016/j.taap.2023.116638.

Kędzierski, Jacek et al. (2023) ‘Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation’, Toxicology Letters, 384, pp. 1–13. Available at: https://doi.org/10.1016/j.toxlet.2023.07.006.

Ben Rhouma, Bochra et al. (2023) ‘Molecular mechanisms underlying the defects of two novel mutations in the HSD17B3 gene found in the Tunisian population.’, The Journal of steroid biochemistry and molecular biology, 227, p. 106235. Available at: https://doi.org/10.1016/j.jsbmb.2022.106235.

Berber, M. et al. (2023) ‘Calcineurin regulates aldosterone production via dephosphorylation of NFATC4’, JCI Insight, 8(14). Available at: https://doi.org/10.1172/jci.insight.157027.

Bolten, Jan Stephan et al. (2023) ‘Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models’, Toxicology and applied pharmacology, (446), p. 116493. Available at: https://doi.org/10.1016/j.taap.2023.116493.

Bourqui, Laurent et al. (2023) ‘A novel mouse model for an inducible gene modification in the renal thick ascending limb.’, American journal of physiology. Renal physiology, 324(5), pp. F446–F460. Available at: https://doi.org/10.1152/ajprenal.00250.2022.

Haedenkamp, Tareq M et al. (2023) ‘Antimicrobial drug use and the risk of glioma: A case-control study.’, Cancer medicine, 12(3), pp. 3684–3695. Available at: https://doi.org/10.1002/cam4.5222.

Jäger, M.-C. et al. (2023) ‘Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays’, Current Research in Toxicology, 5. Available at: https://doi.org/10.1016/j.crtox.2023.100119.

Jäger, Marie-Christin et al. (2023) ‘Extended steroid profiling in H295R cells provides deeper insight into chemical-induced disturbances of steroidogenesis: Exemplified by prochloraz and anabolic steroids.’, Molecular and cellular endocrinology, 570, p. 111929. Available at: https://doi.org/10.1016/j.mce.2023.111929.

Pearson, Adam et al. (2023) ‘Integration of High-Throughput Imaging and Multiparametric Metabolic Profiling Reveals a Mitochondrial Mechanism of Tenofovir Toxicity.’, Function (Oxford, England), 4(1), p. zqac065. Available at: https://doi.org/10.1093/function/zqac065.

Schreier, Verena N. et al. (2023) ‘Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map’, Environment international, 176, p. 107978. Available at: https://doi.org/10.1016/j.envint.2023.107978.

Schreier, V.N., Odermatt, A. and Welle, F. (2023) ‘Migration Modeling as a Valuable Tool for Exposure Assessment and Risk Characterization of Polyethylene Terephthalate Oligomers’, Molecules, 28(1). Available at: https://doi.org/10.3390/molecules28010173.

Wharton, Gerold T et al. (2023) ‘Overview of global real-world data sources for pediatric pharmacoepidemiologic research.’, Pharmacoepidemiology and drug safety, p. doi: 10.1002/pds.5695. Available at: https://doi.org/10.1002/pds.5695.

Becker, Anna M. et al. (2022) ‘Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects’, Clinical Pharmacology & Therapeutics, 111(4), pp. 886–895. Available at: https://doi.org/10.1002/cpt.2487.

Bouitbir, Jamal, Panajatovic, Miljenko V. and Krähenbühl, Stephan (2022) ‘Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line’, International journal of molecular sciences, 23(4), p. 2282. Available at: https://doi.org/10.3390/ijms23042282.

Duthaler, Urs et al. (2022) ‘Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently.’, Clinical pharmacokinetics, pp. 1039–1055. Available at: https://doi.org/10.1007/s40262-022-01119-0.

Gathercole, Laura L et al. (2022) ‘AKR1D1 knockout mice develop a sex-dependent metabolic phenotype.’, The Journal of endocrinology, 253(3), pp. 97–113. Available at: https://doi.org/10.1530/joe-21-0280.

Geueke, Birgit et al. (2022) ‘Systematic evidence on migrating and extractable food contact chemicals: Most chemicals detected in food contact materials are not listed for use.’, Crit Rev Food Sci Nutr., pp. 1–11. Available at: https://doi.org/10.1080/10408398.2022.2067828.

Holze, Friederike et al. (2022) ‘Correction to: Safety pharmacology of acute LSD administration in healthy subjects’, Psychopharmacology, 239(2), p. 661. Available at: https://doi.org/10.1007/s00213-021-05988-4.

Holze, Friederike et al. (2022) ‘Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects’, Neuropsychopharmacology, 47(6), pp. 1180–1187. Available at: https://doi.org/10.1038/s41386-022-01297-2.

Inderbinen, Silvia G et al. (2022) ‘Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters.’, Toxicology, 471, p. 153159. Available at: https://doi.org/10.1016/j.tox.2022.153159.

Keppner, Anna et al. (2022) ‘Androglobin, a chimeric mammalian globin, is required for male fertility.’, eLife, 11, p. 72374. Available at: https://doi.org/10.7554/elife.72374.

Kolaczynska, Karolina E. et al. (2022) ‘Receptor Interaction Profiles of 4-Alkoxy-3,5-Dimethoxy-Phenethylamines (Mescaline Derivatives) and Related Amphetamines’, Frontiers in Pharmacology, 12, p. 794254. Available at: https://doi.org/10.3389/fphar.2021.794254.

Leclercq, Gabrielle et al. (2022) ‘JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy.’, Journal for immunotherapy of cancer, 10(1), p. e003766. Available at: https://doi.org/10.1136/jitc-2021-003766.

Leclercq, Gabrielle et al. (2022) ‘Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils.’, Oncoimmunology, 11(1), p. 2039432. Available at: https://doi.org/10.1080/2162402x.2022.2039432.

Meier, Daniel T et al. (2022) ‘Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing.’, Nature communications, 13(1), p. 4761. Available at: https://doi.org/10.1038/s41467-022-32509-4.

Müller, Felix et al. (2022) ‘Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants’, Psychopharmacology, 239(6), pp. 1933–1943. Available at: https://doi.org/10.1007/s00213-022-06066-z.

Novakova, Katerina et al. (2022) ‘PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle.’, International journal of molecular sciences, 23(20), p. 12304. Available at: https://doi.org/10.3390/ijms232012304.

Nsaibia, Mohamed J et al. (2022) ‘Implication of Lipids in Calcified Aortic Valve Pathogenesis: Why Did Statins Fail?’, Journal of clinical medicine, 11(12), p. 3331. Available at: https://doi.org/10.3390/jcm11123331.

R Charlier, Sarah H et al. (2022) ‘Association between glycemic control and risk of venous thromboembolism in diabetic patients: a nested case-control study.’, Cardiovascular diabetology, 21(1), p. 2. Available at: https://doi.org/10.1186/s12933-021-01432-1.

Roos, Noëmi Johanna et al. (2022) ‘Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines’, Food and Chemical Toxicology, 162, p. 112869. Available at: https://doi.org/10.1016/j.fct.2022.112869.

Schreier, Verena N. et al. (2022) ‘Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: Protocol for a systematic evidence map’, Environment International, 167, p. 107387. Available at: https://doi.org/10.1016/j.envint.2022.107387.

Stücheli, Simon et al. (2022) ‘The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples.’, Cancers, 14(13), p. 3074. Available at: https://doi.org/10.3390/cancers14133074.

Weingartner, Michael et al. (2022) ‘Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection.’, PLoS neglected tropical diseases, 16(1), p. e0009192. Available at: https://doi.org/10.1371/journal.pntd.0009192.

Baier, Felix Alexander et al. (2021) ‘Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine Liver.’, Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745–767. Available at: https://doi.org/10.1016/j.jcmgh.2021.04.003.

Banki, Eszter et al. (2021) ‘Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis.’, Kidney international, 100(4), pp. 850–869. Available at: https://doi.org/10.1016/j.kint.2021.06.030.

Beck, Katharina R. and Odermatt, Alex (2021) ‘Antifungal therapy with azoles and the syndrome of acquired mineralocorticoid excess’, Molecular and Cellular Endocrinology, 524, p. 111168. Available at: https://doi.org/10.1016/j.mce.2021.111168.

Bell, Rachel M B et al. (2021) ‘Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.’, Molecular metabolism, 48, p. 101225. Available at: https://doi.org/10.1016/j.molmet.2021.101225.

Birk, Julia et al. (2021) ‘Monitoring Changes in the Oxidizing Milieu in the Endoplasmic Reticulum of Mammalian Cells Using HyPerER.’, Bio-protocol, 11(13), p. e4076. Available at: https://doi.org/10.21769/bioprotoc.4076.

Charlier, Sarah et al. (2021) ‘Antidiabetic Treatment, Level of Glycemic Control, and Risk of Fracture in Type 2 Diabetes: a Nested, Case-Control Study.’, The Journal of clinical endocrinology and metabolism, 106(2), pp. 554–566. Available at: https://doi.org/10.1210/clinem/dgaa796.

Gómez, Cristina et al. (2021) ‘Impact on Bile Acid Concentrations by Alveolar Echinococcosis and Treatment with Albendazole in Mice.’, Metabolites, 11(7), p. 442. Available at: https://doi.org/10.3390/metabo11070442.

Holze, Friederike et al. (2021) ‘Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin’, Frontiers in Pharmacology, 12, p. 711255. Available at: https://doi.org/10.3389/fphar.2021.711255.

Holze, Friederike et al. (2021) ‘Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide Microdoses in Healthy Participants.’, Clinical pharmacology and therapeutics, 109(3), pp. 658–666. Available at: https://doi.org/10.1002/cpt.2057.

Holze, Friederike et al. (2021) ‘Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects.’, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 46(3), pp. 537–544. Available at: https://doi.org/10.1038/s41386-020-00883-6.

Hutten, Nadia R. P. W. et al. (2021) ‘Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers’, ACS pharmacology & translational science, 4(2), pp. 461–466. Available at: https://doi.org/10.1021/acsptsci.0c00099.

Inderbinen, Silvia G. et al. (2021) ‘Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole’, Toxicology and applied pharmacology, 412, p. 115387. Available at: https://doi.org/10.1016/j.taap.2020.115387.

Kolaczynska, Karolina E, Liechti, Matthias E and Duthaler, Urs (2021) ‘Development and validation of an LC-MS/MS method for the bioanalysis of psilocybin’s main metabolites, psilocin and 4-hydroxyindole-3-acetic acid, in human plasma.’, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1164, p. 122486. Available at: https://doi.org/10.1016/j.jchromb.2020.122486.

Kolaczynska, Karolina E. et al. (2021) ‘The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative’, International journal of molecular sciences, 22(15), p. 8277. Available at: https://doi.org/10.3390/ijms22158277.

Leclercq, Gabrielle et al. (2021) ‘Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodies.’, Journal for immunotherapy of cancer, 9(7), p. e002582. Available at: https://doi.org/10.1136/jitc-2021-002582.

Lemmens, Myriam et al. (2021) ‘Evaluation of two; in vitro; assays for tumorigenicity assessment of CRISPR-Cas9 genome-edited cells.’, Molecular therapy. Methods & clinical development, 23, pp. 241–253. Available at: https://doi.org/10.1016/j.omtm.2021.09.004.

Liechti, Matthias E. and Holze, Friederike (2021) ‘Dosing Psychedelics and MDMA’, Current topics in behavioral neurosciences, p. in press. Available at: https://doi.org/10.1007/7854_2021_270.

Müller, Felix et al. (2021) ‘MDMA-induced changes in within-network connectivity contradict the specificity of these alterations for the effects of serotonergic hallucinogens.’, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 46(3), pp. 545–553. Available at: https://doi.org/10.1038/s41386-020-00906-2.

Noseda, Roberta et al. (2021) ‘MDMA-related presentations to the emergency departments of the European Drug Emergencies Network plus (Euro-DEN Plus) over the four-year period 2014-2017.’, Clinical toxicology (Philadelphia, Pa.), 59(2), pp. 131–137. Available at: https://doi.org/10.1080/15563650.2020.1784914.

Panajatovic, Miljenko V. et al. (2021) ‘Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression’, International Journal of Molecular Siences, 22(9), p. 4950. Available at: https://doi.org/10.3390/ijms22094950.

Ramaekers, Johannes G. et al. (2021) ‘A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers’, Journal of Psychopharmacology, 35(4), pp. 398–405. Available at: https://doi.org/10.1177/0269881120940937.

Rudin, Deborah, Liechti, Matthias E. and Luethi, Dino (2021) ‘Molecular and clinical aspects of potential neurotoxicity induced by new psychoactive stimulants and psychedelics’, Experimental Neurology, 343, p. 113778. Available at: https://doi.org/10.1016/j.expneurol.2021.113778.

Sanvee, Gerda M et al. (2021) ‘mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle - Roles of Rap1 geranylgeranylation and mitochondrial dysfunction.’, Biochemical pharmacology, 192, p. 114750. Available at: https://doi.org/10.1016/j.bcp.2021.114750.

Schmid, Yasmin et al. (2021) ‘Acute subjective effects in LSD- and MDMA-assisted psychotherapy.’, Journal of psychopharmacology (Oxford, England), 35(4), pp. 362–374. Available at: https://doi.org/10.1177/0269881120959604.

Schnoz, Christina et al. (2021) ‘Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC’, Pflügers Archiv : European journal of physiology, 473(1), pp. 79–93. Available at: https://doi.org/10.1007/s00424-020-02491-1.

Vanderriele, Paul-Emmanuel et al. (2021) ‘Salt-Sensitive Hypertension in GR; +/-; Rats Is Accompanied with Dysregulation in Adrenal Soluble Epoxide Hydrolase and Polyunsaturated Fatty Acid Pathways.’, International journal of molecular sciences, 22(24), p. 13218. Available at: https://doi.org/10.3390/ijms222413218.

Vizeli, Patrick et al. (2021) ‘Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis’, Scientific reports, 11(1), p. 10851. Available at: https://doi.org/10.1038/s41598-021-90343-y.

Weingartner, Michael et al. (2021) ‘The ratio of ursodeoxycholyltaurine to 7-oxolithocholyltaurine serves as a biomarker of decreased 11β-hydroxysteroid dehydrogenase 1 activity in mouse’, Brit. J. Pharmacol, pp. 3309–3326. Available at: https://doi.org/10.1111/bph.15367.

Anssar, Tareq M et al. (2020) ‘Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma.’, Cancer medicine, 9(3), pp. 1263–1275. Available at: https://doi.org/10.1002/cam4.2767.

Becker, Claudia et al. (2020) ‘Use of selective serotonin reuptake inhibitors, other antidepressant medication, and risk of cataract: a case-control study based on Swiss claims data’, European Journal of Clinical Pharmacology, 76(9), pp. 1329–1335. Available at: https://doi.org/10.1007/s00228-020-02923-y.

Beck, Katharina R. et al. (2020) ‘Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals’, The Journal of steroid biochemistry and molecular biology, 199, p. 105605. Available at: https://doi.org/10.1016/j.jsbmb.2020.105605.

Beck, Katharina R., Thompson, George R. and Odermatt, Alex (2020) ‘Drug-induced endocrine blood pressure elevation’, Pharmacological Research, 154, p. 104311. Available at: https://doi.org/10.1016/j.phrs.2019.104311.

Davis, Matthew R. et al. (2020) ‘Management of posaconazole-induced pseudohyperaldosteronism’, Journal of Antimicrobial Chemotherapy, 75(12), pp. 3688–3693. Available at: https://doi.org/10.1093/jac/dkaa366.

Gómez, Cristina et al. (2020) ‘Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples’, Metabolites, 10(7), p. 282. Available at: https://doi.org/10.3390/metabo10070282.

Grafinger, Katharina Elisabeth, Liechti, Matthias E. and Liakoni, Evangelia (2020) ‘Clinical value of analytical testing in patients presenting with new psychoactive substances intoxication’, British Journal of Clinical Pharmacology, 86(3), pp. 429–436. Available at: https://doi.org/10.1111/bcp.14115.

Holze, Friederike et al. (2020) ‘Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects’, Neuropsychopharmacology, 45(3), pp. 462–471. Available at: https://doi.org/10.1038/s41386-019-0569-3.

Hutten, Nadia R P W et al. (2020) ‘Mood and cognition after administration of low LSD doses in healthy volunteers: A placebo controlled dose-effect finding study.’, European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 41, pp. 81–91. Available at: https://doi.org/10.1016/j.euroneuro.2020.10.002.

Ilic, Marija et al. (2020) ‘Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of; In Vitro; Methods to Assess the Potency of Drugs That Target Monoamine Transporters.’, Frontiers in pharmacology, 11, p. 673. Available at: https://doi.org/10.3389/fphar.2020.00673.

Inderbinen, Silvia G. et al. (2020) ‘Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α’, Toxicology letters, 322, pp. 39–49. Available at: https://doi.org/10.1016/j.toxlet.2020.01.001.

Lizák, Beáta et al. (2020) ‘Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione’, BMC Biology, 18(1), p. 19. Available at: https://doi.org/10.1186/s12915-020-0749-y.

Luethi, Dino and Liechti, Matthias E. (2020) ‘Designer drugs: mechanism of action and adverse effects’, Archives of Toxicology, 94(4), pp. 1085–1133. Available at: https://doi.org/10.1007/s00204-020-02693-7.

Mayr, Fabian et al. (2020) ‘Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction’, International Journal of Molecular Sciences, 21(19), p. 7102. Available at: https://doi.org/10.3390/ijms21197102.

Mégarbane, Bruno et al. (2020) ‘The neurobehavioral effects of the designer drug naphyrone - an experimental investigation with pharmacokinetics and concentration/effect relationship in mice.’, Psychopharmacology, 237(7), pp. 1943–1957. Available at: https://doi.org/10.1007/s00213-020-05510-2.

Müller, Felix et al. (2020) ‘Treatment of a Complex Personality Disorder Using Repeated Doses of LSD-A Case Report on Significant Improvements in the Absence of Acute Drug Effects.’, Frontiers in psychiatry, 11, p. 573953. Available at: https://doi.org/10.3389/fpsyt.2020.573953.

Nguyen, Minh-Vu H. et al. (2020) ‘Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism’, Clinical Infectious Diseases, 70(12), pp. 2593–2598. Available at: https://doi.org/10.1093/cid/ciz741.

Patt, Melanie et al. (2020) ‘Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis’, Biochemical pharmacology, 172, p. 113781. Available at: https://doi.org/10.1016/j.bcp.2019.113781.

Patt, Melanie et al. (2020) ‘Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211’, Molecular and cellular endocrinology, 518, p. 110873. Available at: https://doi.org/10.1016/j.mce.2020.110873.

Potashkin, Judy et al. (2020) ‘Understanding the links between cardiovascular disease and Parkinson’s disease’, Movement disorders : official journal of the Movement Disorder Society, 35(1), pp. 55–74. Available at: https://doi.org/10.1002/mds.27836.

Randi, Elisa B. et al. (2020) ‘The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease’, Antioxidants & redox signaling, 32(16), pp. 1155–1171. Available at: https://doi.org/10.1089/ars.2019.7868.

Schmid, Yasmin et al. (2020) ‘Emergency department presentations related to acute toxicity following recreational use of cannabis products in Switzerland’, Drug and Alcohol Dependence, 206, p. 107726. Available at: https://doi.org/10.1016/j.drugalcdep.2019.107726.

Schulze, Friederike et al. (2020) ‘Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes’, Scientific Reports, 10(1), p. 3035. Available at: https://doi.org/10.1038/s41598-020-59701-0.

Steuer, Andrea E et al. (2020) ‘Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans.’, Metabolites, 10(8), p. 0306. Available at: https://doi.org/10.3390/metabo10080306.

Thompson, George R., Surampudi, Prasanth N. and Odermatt, Alex (2020) ‘Gynecomastia and hypertension in a patient treated with posaconazole’, Clinical case reports, 8(12), pp. 3158–3161. Available at: https://doi.org/10.1002/ccr3.3376.

Tsachaki, Maria et al. (2020) ‘Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration’, Cellular and Molecular Life Sciences, 77(6), pp. 1153–1175. Available at: https://doi.org/10.1007/s00018-019-03227-w.

Akram, Muhammad et al. (2019) ‘Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase’, Journal of Steroid Biochemistry and Molecular Biology, 192, p. 105358. Available at: https://doi.org/10.1016/j.jsbmb.2019.04.007.

Becker, Claudia, Jick, Susan S. and Meier, Christoph R. (2019) ‘ACE inhibitor use and risk of cataract: a case-control analysis’, The British journal of ophthalmology, 103(11), pp. 1561–1565. Available at: https://doi.org/10.1136/bjophthalmol-2018-312980.

Beck, Katharina R. et al. (2019) ‘11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ’, Journal of Lipid Research, 60, pp. 1535–1546. Available at: https://doi.org/10.1194/jlr.m092908.

Beck, Katharina R. et al. (2019) ‘Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2’, The Journal of steroid biochemistry and molecular biology, 190, pp. 19–28. Available at: https://doi.org/10.1016/j.jsbmb.2019.03.011.

Boccard, Julien et al. (2019) ‘Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening’, Talanta, 195, pp. 77–86. Available at: https://doi.org/10.1016/j.talanta.2018.11.019.

Bühler, Tim, Schmid, Yasmin and Liechti, Matthias E. (2019) ‘Verdacht auf K.o.-Mittel: Diagnostik in der Notfallstation und Praxis’, Praxis, 108(13), pp. 869–876. Available at: https://doi.org/10.1024/1661-8157/a003306.

Canonica, Jérémie et al. (2019) ‘Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl- Cotransporter NCC and Transiently Affects Sodium Handling’, Frontiers in physiology, 10, p. 989. Available at: https://doi.org/10.3389/fphys.2019.00989.

Crane, Erika A. et al. (2019) ‘Profiling withanolide A for therapeutic targets in neurodegenerative diseases’, Bioorganic & medicinal chemistry, 27(12), pp. 2508–2520. Available at: https://doi.org/10.1016/j.bmc.2019.03.022.

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